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Mushtaq Bilal, PhDResearcher @ Syddansk Universitet
Mushtaq Bilal, PhDResearcher @ Syddansk UniversitetLoved by 1 million+ researchers from
Popular papers to read
Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer
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Top papers of 2023
List of pathways analyzed for GSEA from Genomic Landscape of <i>CXCR4</i> Mutations in Waldenström Macroglobulinemia
31 Mar 2023
In this paper , the authors present a list of pathways analyzed for GSEA and show that GSEA is a GSEA-like pathway for the GSEA pathway analysis task, i.e.Data from Preclinical and Pilot Study of Type I FLT3 Tyrosine Kinase Inhibitor, Crenolanib, with Sorafenib in Acute Myeloid Leukemia and <i>FLT3</i>-Internal Tandem Duplication
31 Mar 2023
In this paper , the authors evaluated the safety, activity, and emergence of FLT3-KD mutations with combination therapy of crenolanib and sorafenib in acute myeloid leukemia (AML).Data from Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor
31 Mar 2023
In this article , a compound Ia was developed to address the limitations of available BRAFi/MEKi, which demonstrated high central nervous system penetration and triggered evident superiority over approved BRAFi in a macro-metastatic and in a disseminated micro-metastic brain model.Data from Preclinical Evaluation of Nilotinib Efficacy in an Imatinib-Resistant KIT-Driven Tumor Model
31 Mar 2023
In this paper , the authors investigated the effect of nilotinib against cells expressing imatinib-sensitive or IMATI-resistant KIT mutations and evaluated fluorodeoxyglucose-positron emission tomography (FDG-PET) imaging as a biomarker of nil-otinib response.Data from Cytotoxicity of the matrix metalloproteinase–activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells
31 Mar 2023
In this article , the toxicity of matrix metalloproteinase-activated Anthrax lethal toxin (LeTx) is shown to be dependent on host cell surface MMP 2 and MMP 9 activity as well as the presence of the activating V600E B-RAF mutation.Data from High Detection Rates of Pancreatic Cancer Across Stages by Plasma Assay of Novel Methylated DNA Markers and CA19-9
31 Mar 2023
In this article , the authors used target enrichment long-probe quantitative amplified signal method to identify tissue methylated DNA markers (MDMs) associated with pancreatic ductal adenocarcinoma (PDAC).Data from Increased cyclin D1 expression can mediate BRAF inhibitor resistance in <i>BRAF</i> V600E–mutated melanomas
31 Mar 2023
In this article , the authors address whether dysregulation of cyclin-dependent kinase 4 (CDK4) and/or cyclin D1 contribute to the BRAF inhibitor resistance of melanoma cells.Data from Molecular Characterization and Prospective Evaluation of Pathologic Response and Outcomes with Neoadjuvant Therapy in Metaplastic Triple-Negative Breast Cancer
31 Mar 2023
In this paper , the authors analyzed the rate of pathologic complete response (pCR) to neoadjuvant therapy, survival outcomes, and genomic and transcriptomic profiles of the pretreatment tumors in a prospective clinical trial.Data from Nitro-chloromethylbenzindolines: hypoxia-activated prodrugs of potent adenine <i>N</i>3 DNA minor groove alkylators
31 Mar 2023
In this article , a class of prodrugs, nitro-chloromethylindolines, which undergo hypoxia-selective activation by endogenous nitroreductases in tumor cells to form the corresponding amino compounds were described.Data from Phase I Clinical Trial of DNA Methyltransferase Inhibitor Decitabine and PARP Inhibitor Talazoparib Combination Therapy in Relapsed/Refractory Acute Myeloid Leukemia
31 Mar 2023
In this article , a phase I clinical trial combining DNMTi decitabine and the PARPi talazoparib in relapsed/refractory acute myeloid leukemia (AML) was reported.Data from Phase Ib Dose Expansion and Translational Analyses of Olaparib in Combination with Capivasertib in Recurrent Endometrial, Triple-Negative Breast, and Ovarian Cancer
31 Mar 2023
Olaparib and capivasertib were evaluated in endometrial, triple-negative breast, ovarian, fallopian tube, or peritoneal cancer as mentioned in this paper , and the combination was associated with no serious adverse events.Data from Comprehensive Genome Profiling in Patients With Metastatic Non–Small Cell Lung Cancer: The Precision Medicine Phase II Randomized SAFIR02-Lung Trial
31 Mar 2023
The SAFIR02-Lung trial as discussed by the authors was an open-label, randomized, phase II trial, involving 33 centers in France, and the primary outcome was progression-free survival (PFS).Data from Comprehensive Analysis of R-Spondin Fusions and <i>RNF43</i> Mutations Implicate Novel Therapeutic Options in Colorectal Cancer
31 Mar 2023
In this paper , gene fusions involving R-spondin have been shown to drive Wnt-dependent tumor initiation in colorectal cancer and mutations have been detected in 1.4% of colortal cancer cases compared with wild-type (WT) cases.Data from Serum Concentration of CD137 and Tumor Infiltration by M1 Macrophages Predict the Response to Sintilimab plus Bevacizumab Biosimilar in Advanced Hepatocellular Carcinoma Patients
31 Mar 2023
Cappuyns et al. as mentioned in this paper investigated the biomarkers of sintilimab (anti-PD-1) plus IBI305 (a bevacizumab biosimilar) in advanced hepatocellular carcinoma (HCC), as well as their safety and efficacy.Data from Identification of <i>LIV1</i>, a Putative Zinc Transporter Gene Responsible for HDACi-Induced Apoptosis, Using a Functional Gene Screen Approach
31 Mar 2023
In this paper , a functional gene screen approach named suppression of mortality by antisense rescue technique was used to identify the key genes responsible for the tumor-selective killing trichostatin A. Over 20 genes associated with HDACi-induced mortality were identified.Data from Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays
31 Mar 2023
P Pollyea et al. as mentioned in this paper identified and quantified mutations in genes known to be frequently altered in clonal hematopoiesis, such as DNMT3A, TET2, ASXL1, TP53, ATM, CHEK2, SF3B1, CBL, JAK2, and CBL-JAK2.Data from Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Patients With <i>NTRK</i> Fusion-Positive Solid Tumors
31 Mar 2023
In this article , entrectinib has been shown to significantly inhibit tropomyosin receptor kinases (TRKAs)/B/C and ROS1 in adults with fusion-positive solid tumors from three phase I/II trials.Data from Dose Escalation Data from the Phase 1 Study of the Liposomal Formulation of Eribulin (E7389-LF) in Japanese Patients with Advanced Solid Tumors
31 Mar 2023
In this paper , the authors report the dose-escalation part of a phase I study of liposomal eribulin (E7389-LF) in Japanese patients with advanced solid tumors and no alternative standard therapy.Data from <i>BRCA2</i>, <i>ATM</i>, and <i>CDK12</i> Defects Differentially Shape Prostate Tumor Driver Genomics and Clinical Aggression
31 Mar 2023
In this article , the authors performed targeted sequencing of 1,615 plasma cell-free DNA samples from 879 patients with metastatic prostate cancer and used split-read structural variation analysis to characterize tumor suppressor rearrangements.Data from MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma
31 Mar 2023
In this article , the authors show that endogenous MYC protects pancreatic ductal adenocarcinoma (PDAC) driven by KRAS and G12D from eradication by the immune system.Table S4 from Aquaporin-7 Regulates the Response to Cellular Stress in Breast Cancer
31 Mar 2023
In this article , the authors present raw data and heat maps for metabolomics of cell lines and tumors. But they do not provide any analysis of the data sets themselves, only the heat maps.Supplementary Materials and Methods from Antitumor Effects of Anti-Semaphorin 4D Antibody Unravel a Novel Proinvasive Mechanism of Vascular-Targeting Agents
31 Mar 2023
In this article , the authors proposed a method to solve the problem of self-diagnosis of cancer using medical data from cancer patients' medical records, and showed that it works well.Supplementary Table 2 from Differences in the Transcriptional Response to Fulvestrant and Estrogen Deprivation in ER-Positive Breast Cancer
31 Mar 2023
In this article , a comparative analysis of transcripts and Gene Ontology functional sets resulting from comparative analyses is presented. But this analysis is restricted to gene ontology and is not applicable to other types of transcripts.Supplementary Figure 3 from Deciphering the Mechanisms of Tumorigenesis in Human Pancreatic Ductal Epithelial Cells
31 Mar 2023
In this paper , the authors confirmed gene expression change of BMP7 and GRB10 in cDNA microarray analysis, and used this information to identify gene expression changes in cDNs.Supplementary Figures 4 - 8 from Arylsulfonamide KCN1 Inhibits <i>In Vivo</i> Glioma Growth and Interferes with HIF Signaling by Disrupting HIF-1α Interaction with Cofactors p300/CBP
31 Mar 2023
In this article , the authors showed that chronic systemic KCN1 administration shows little effect on major organs, except liver, except major organs except liver liver, of mice with orthotopic (intracranial) brain tumor models.Supplementary Figure 3 from EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors
31 Mar 2023
In this paper , a wound healing test was performed to assess the impact of EMD 1214063 (A) and EMD 1204831 (B) on tumor cell migration.Supplementary Table 1 from BET Bromodomain Inhibition of <i>MYC</i>-Amplified Medulloblastoma
31 Mar 2023
In this article , Nanostring CNV of MB002 and MB004 was used to detect the presence of a virus in the MB002 data set and the MB004 data set.Supplementary Figure 3 from Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
31 Mar 2023
In this article , OPN was used to promote clonogenicity of HT-29 cells on different levels of OPN in different concentrations, and the results showed that OPN promoted clonogenesis of HT29 cells.Supplementary Tables and Figures from Ibrutinib Therapy Releases Leukemic Surface IgM from Antigen Drive in Chronic Lymphocytic Leukemia Patients
31 Mar 2023
In this paper , the authors present Table 1-S2 and Figures S1-S4 with legends, and Table 2-S3 and Table 4-S5 with legends.Supplementary Figure 4 from A Peptide-Based Positron Emission Tomography Probe for <i>In Vivo</i> Detection of Caspase Activity in Apoptotic Cells
31 Mar 2023
Semi-quantitative analysis of cleaved caspase-3 histological samples of DLD-1 and SW620 xenograft tumors treated with vehicle or AZD-1152 was performed in this paper .Supplementary Figure 1 from Ketogenic Diets Enhance Oxidative Stress and Radio-Chemo-Therapy Responses in Lung Cancer Xenografts
31 Mar 2023
In this paper , the mouse weights were calculated based on the number of mouse heads and the mouse's head width, and the weight of the mouse was calculated.<p>Supplementary Figure 1 - PDF file 911K, Mouse weightsFigure S4 from A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found <i>In Vivo</i>
31 Mar 2023
In this article , the SOX2 and OLIG2 expression in spheres and organoids is discussed. And the authors propose a method to detect SOX 2 expression in organoids.Figure S2 from The Autotaxin—Lysophosphatidic Acid Axis Promotes Lung Carcinogenesis
31 Mar 2023
For example, decreased ENPP2 mRNA expression in human lung cancer was found to be associated with decreased lung cancer survival as mentioned in this paper . But, it was not shown to cause lung cancer metastasis.Table S4 from Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish
31 Mar 2023
In this article , the characteristics of established melanoma cell lines were used to evaluate the effectiveness of existing cell lines for melanoma diagnosis and treatment.<p>Characteristics of established cell lines utilised in this studySupplementary Figure 2 from JMJD2B Promotes Epithelial–Mesenchymal Transition by Cooperating with β-Catenin and Enhances Gastric Cancer Metastasis
31 Mar 2023
In this article , JMJD2B stimulates TCF/Beta-catenin-dependent transcription, and it is shown to stimulate TCF and Beta-Catenin dependent transcription.Supplementary Figure S2 from Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer
31 Mar 2023
In this paper , the association between histone mRNA and miR-760 in GC cells was investigated and shown to be statistically significant in terms of the number of histone mutations.Supplementary Figure S4 from Epigenetic Inactivation of microRNA-34b/c Predicts Poor Disease-Free Survival in Early-Stage Lung Adenocarcinoma
31 Mar 2023
In this paper , Kaplan-Meier plots of DFS and OS according to miR-34b/c methylation in 140 early stage lung AC patients were used to compare the two groups.Supplementary Figure 4 from Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells
31 Mar 2023
In this paper , the function of ROR1-CAR and CD19-CAR modified CD8+ T-cells against primary CLL is augmented by CAR modified CD4+ helper Tcells.Supplement Figure 3 from Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study
31 Mar 2023
In this article , the authors proposed a method to solve the problem of the "missing link" problem in the context of data augmentation, and presented a method for solving it.Supplementary Figure 2 from A Tumorigenic Factor Interactome Connected through Tumor Suppressor MicroRNA-198 in Human Pancreatic Cancer
31 Mar 2023
In this paper , the predicted targets for miR-198 are predicted for PBX-1, VCP, and VCP-1 and are presented in a PDF file.Figure S4 from HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy–Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout Mice
31 Mar 2023
In this paper , a novel uveal melanoma PDX model using clinical grade melanoma markers is presented. But the model is not suitable for the detection of melanoma.Supplemental Figure 3 from Mesenchymal Stem Cells from Human Fat Engineered to Secrete BMP4 Are Nononcogenic, Suppress Brain Cancer, and Prolong Survival
31 Mar 2023
In this article , the authors used hAMSCs-BMP4 to promote differentiation of BTICs in vitro, and showed that the hamSCs can promote BTIC differentiation in vitro.Supplementary Figure 1 from DNA Demethylating Agents Synergize with Oncolytic HSV1 against Malignant Gliomas
31 Mar 2023
In this article , Methylated CpG sites in the Nestin promoter region of rQNestin34.5, immediately upstream of the gamma1 34.5 gene were identified.Supplementary Figures 1 - 3 from Biologic Effects of Platelet-Derived Growth Factor Receptor α Blockade in Uterine Cancer
31 Mar 2023
In this article , in vivo therapeutic and biological effects of PDGFRalpha blockade (3G3) on uterine cancer were investigated. And they showed that angiogenesis factors were down-regulated by 3G3 treatment in PDGFCalpha-positive cells and PDGfrα-negative cells.Supplementary Figure 1 from Cabozantinib Suppresses Tumor Growth and Metastasis in Hepatocellular Carcinoma by a Dual Blockade of VEGFR2 and MET
31 Mar 2023
In this article , the authors report that sorafenib-resistant HCC specimens exhibit higher p-MET-positive rate compared with sensitive HCC samples, which is a sign that they are more sensitive to HCC.Supplementary Figure 3 from hTERT Inhibition Triggers Epstein–Barr Virus Lytic Cycle and Apoptosis in Immortalized and Transformed B Cells: A Basis for New Therapies
31 Mar 2023
In this paper , hTERT inhibition promotes AKT1/FOXO3/NOXA-dependent apoptosis in 69K, 69K+HTERT inhibited hTERTs.Supplementary Figure 1 from Identifying and Targeting <i>ROS1</i> Gene Fusions in Non–Small Cell Lung Cancer
31 Mar 2023
In this article , micrographs of H&E and IHC of two squamous cell ROS1 positive cases are presented, along with a detailed description of the two cases.Table S6 from MicroRNA Array Analysis Finds Elevated Serum miR-1290 Accurately Distinguishes Patients with Low-Stage Pancreatic Cancer from Healthy and Disease Controls
31 Mar 2023
In this article , the performance of microRNAs measured by Taqman real-time PCR assays was investigated. But the results were limited to the case of microRNA.Top papers of 2022
Photothermal converting polypyrrole/polyurethane composite foams for effective solar desalination
01 Apr 2022 - Desalination
In this paper , a lightweight commercial polyurethane foam (PUF) was chosen as the support modified with a black polypyrrole (PPy) layer to obtain a simple and effective photothermal conversion "black foam" (Py-PUF).The role of carbon capture, utilization, and storage for economic pathways that limit global warming to below 1.5°C
01 Apr 2022 - iScience
In this article , a sensible strategy to prevent climate change begins by mitigating emission sources requiring the least energy and capital investment per ton of CO2, such as new emitters and long-term stationary sources.Agency MBS as Safe Assets
01 Apr 2022 - Social Science Research Network
In this paper , the authors measured as yield spreads against AAA corporate bonds, the convenience premium for agency MBS averaged 47 basis points between 1995 and 2021, about half of the long-term Treasury convenience premium, which is consistent with a prepayment-driven demand channel.Rational synthesis of rare-earth lanthanum molybdate covered reduced graphene oxide nanocomposites for the voltammetric detection of Moxifloxacin hydrochloride.
01 Apr 2022 - Bioelectrochemistry
In this article , the rare earth mixed metal molybdate covered reduced graphene oxide La2(MoO4)3@rGO nanocomposites by a simple hydrothermal method for the sensitive detection of Moxifloxacin hydrochloride (MOF) in pharmaceutical and human urine samples.The importance of hydrogen for energy diversity of Turkey's energy production: 2030 projection
01 Apr 2022 - International Journal of Hydrogen Energy
In this paper , the authors evaluated hydrogen in terms of energy diversity until 2030 with EnergyPlan software and determined the reduction in the amount of emissions and costs by mixing hydrogen into the natural gas pipelines by 5-10 and 20% by volume by producing electrolyzers with photovoltaic systems.Fermentation Quality and Bacterial Ecology of Grass Silage Modulated by Additive Treatments, Extent of Compaction and Soil Contamination
01 Apr 2022 - Fermentation
In this paper , the authors evaluated how management conditions during silage making manipulate the profile of bacterial communities and fermentation quality of grass silages using two compaction levels: tight compaction and loose compaction.Dramatic decrease of secondary organic aerosol formation potential in Beijing: Important contribution from reduction of coal combustion emission.
01 Apr 2022 - Science of The Total Environment
In this paper , the authors reported the sharp decline of secondary organic aerosol formation potential (SOAFP) between two consecutive winters in Beijing and analyzed the reasons for the decrease in SOAFP.To the emergency room and back again: Circular healthcare pathways for acute functional neurological disorders
01 Apr 2022 - Journal of the Neurological Sciences
In this paper , the authors describe patient pathways through healthcare events, and factors affecting risk of emergency department (ED) reattendance, for people presenting acutely with functional neurological disorders.Living with Rheumatic Heart Disease at the Intersection of Biomedical and Aboriginal Worldviews
01 Apr 2022 - International Journal of Environmental Research and Public Health
The findings reveal fundamental differences between Aboriginal and biomedical worldviews contributing to the failure of current approaches to communicating health messages and targeted recommendations for culturally responsive health encounters are provided.Nonlinear bending behavior of a multilayer copper conductor in a dynamic power cable
01 Apr 2022 - Ocean Engineering
In this article , the nonlinear bending properties of multilayer helically wound copper conductors are studied by experiments and numerical simulation, and the results from the finite element model were compared with the experimental data.Project-oriented agency and regeneration in socio-technical transition: Insights from the case of numerical weather prediction (1978–2015)
01 Apr 2022 - Research policy
In this paper , the authors analyze the unfolding of socio-technical transition (STT) using the multi-level perspective (MLP) framework and propose a process model of project-oriented agency that accounts for the role of the reverse salient in the regeneration pathway.Preoperative Low Prealbumin Is Associated With Recurrence in Patients With Stage II/III Gastric Cancer After Laparoscopic D2 Gastrectomy
01 Apr 2022 - Frontiers in Surgery
The findings revealed that nutritional status was an independent predictive factor for recurrence in patients with gastric cancer after D2 gastrectomy, and it is suggested that patients with risk factors forRecurrence receive both nutritional support and intense surveillance.Identification of autosomal recessive novel genes and retinal phenotypes in members of the solute carrier (SLC) superfamily.
Talya Millo, Antonio Rivera, Alexey Obolensky, Devora Marks-Ohana, Mingchu Xu, Yumei Li, Enosh Wilhelm, Prakadeeswari Gopalakrishnan, Menachem Gross, Boris Rosin, Mor Hanany, Andrew R. Webster, Anna M Tracewska, Robert K. Koenekoop, Rui Chen, Gavin Arno, Ora Schueler-Furman, Susanne Roosing, Eyal Banin, Dror Sharon
01 Apr 2022 - Genetics in Medicine
In this article , the clinical and genetic aspects of solute carrier (SLC) genes in inherited retinal diseases (IRDs) were investigated, and a comprehensive analysis of 433 SLC genes in 913 exome sequencing IRD samples was conducted.Physical activity levels and shoulder pain in wheelchair users during COVID-19 restrictions
01 Apr 2022 - Disability and Health Journal
In this article , the authors investigated whether restrictions to limit the spread of the COVID-19 virus affected physical activity, wheelchair use and shoulder pain in manual wheelchair users, and found no significant change in physical activity during lockdown.Preparation of infrared high radiation coatings from modified spinel NiFe2O4 and its energy saving applications
01 Apr 2022 - Ceramics International
In this article , the effect of Cr3+ and Cu2+ doping on the infrared emissivity of spinel NiFe2O4 was investigated and energy saving assessment was carried out in a resistance furnace.An insight into the performance of CNT-based membrane with the application of electric field for distillation process
01 Apr 2022 - Desalination
In this paper , a composite membrane was fabricated by coating carbon nanotubes (CNT), and an electric-enhanced direct contact MD was developed subsequently with the application of alternating current potential (AC).Improving potency of Nanoliposomal AE36 peptide vaccine by adding CD4+ T cell helper epitope and MPL in TUBO breast cancer mice model
01 Apr 2022 - Journal of Drug Delivery Science and Technology
In this paper , a liposomal-based peptide vaccine composed of AE36 (HER2/neu)-derived peptide and PADRE (Pan HLA-DR peptide) as well as monophosphoryl lipid A (MPLA) adjuvant was evaluated in BALB/c mice breast cancer models bearing TUBO tumors.Longitudinal QTc stability and impact of baseline cardiac rhythm on discharge dose in dofetilide‐treated patients
01 Apr 2022 - Journal of Cardiovascular Electrophysiology
The purpose of this study was to evaluate the impact of baseline rhythm on dofetilide dosing during initiation and assess the longitudinal stability of QTc‐all (Bazzett, Fridericia, Framingham, and Hodges) over time.Angiogenic T Cells: Potential Biomarkers for the Early Diagnosis of Interstitial Lung Disease in Autoimmune Diseases?
Verónica Pulito-Cueto, Sara Remuzgo-Martínez, Fernanda Genre, Belén Atienza-Mateo, Víctor M. Mora-Cuesta, David Iturbe-Fernández, Leticia Lera-Gómez, Javier Rodríguez-Carrio, Diana Prieto-Peña, Virginia Portilla, Ricardo Blanco, Alfonso Corrales, Oreste Gualillo, José M. Cifrián, Raquel López-Mejías, Miguel A. González-Gay
01 Apr 2022 - Advances in Cardiovascular Diseases
The findings suggest TAng as potential biomarkers for the early diagnosis of ILD in AD, being in both cases lower than that observed in AD-ILD− and HC.Prognostic factors and clinical features in metacarpophalangeal joint hyperextension after ligament reconstruction with trapeziectomy: A retrospective cohort study.
01 Apr 2022 - Journal of Orthopaedic Science
In this paper , the authors investigated the functional outcomes of patients who underwent surgery for CMC arthritis at two institutions from 2016 to 2020 and determined the pre-operative MCP joint angle that can predict poor outcomes.Peptide-based drug-delivery systems: A new hope for improving cancer therapy
01 Apr 2022 - Journal of Drug Delivery Science and Technology
The usage of peptide-based drug-delivery systems (PBDs) is a strategy in which peptides carry a variety of compounds with pharmacological activity into cells as mentioned in this paper .Introspective knowledge by acquaintance
01 Apr 2022 - Synthese
The authors argue that introspective knowledge by acquaintance is a sui generis kind of knowledge: it is irreducible to any sort of propositional knowledge and is wholly constituted (rather than merely enabled) by a relationship of introspective acquaintance.Design, synthesis and preclinical evaluation of bio-conjugated amylinomimetic peptides as long-acting amylin receptor agonists.
01 Apr 2022 - European journal of medicinal chemistry
In this article , the authors described the development of prototypical long-acting amylin analogue bioconjugates, in which pramlintide's disulfide-linked macrocycle was replaced by a cyclic thioether motif.National Academies Report Calls for Substantial Reforms for US Nursing Homes.
01 Apr 2022 - JAMA health forum
The way in which care in US nursing homes is funded, delivered, and regulated is ineffective, inefficient, fragmented, and unsustainable and requires immediate action to make comprehensive changes as mentioned in this paper .Information Freshness in Uplink OFDM Based Multiple Access Networks in Flat Nakagami-$m$ Fading Channels
01 Apr 2022 - IEEE Transactions on Vehicular Technology
In flat Nakagami-$m$ fading channels, an alternating optimization algorithm is proposed to solve the total information freshness maximization problem andumerical results illustrate that the proposed updating scheme is superior to the rate proportional and rate inverse proportional updating schemes.A novel automatic flow-batch extraction induced by emulsion breaking platform for on-line copper determination in edible oil samples by atomic absorption spectrometry.
01 Apr 2022 - Talanta
In this article , an automatic flow-batch platform coupled with atomic spectrometry for on-line acidic extraction induced by emulsion breaking with heating (FB-EIEBH) for metal determination in edible oils (corn, sunflower and olive oil), was developed for the first time.Assessment of ultra-structure, viability and function of lipopolysaccharides-stimulated human dermal fibroblasts treated with chrysin and exosomes (in vitro study)
01 Apr 2022 - The Saudi Dental Journal
In this article , the authors assessed the role of chrysin and BM-MSC exosomes on ultra-structure, viability and function of human dermal fibroblasts-adult (HDFa) stimulated by LPS.Inflammatory Bowel Disease Management during the COVID-19 Pandemic: A Literature Review
01 Apr 2022 - Middle East Journal of Digestive Diseases
unique concerns about IBD risk in the population as well as management of the disease, and the effectiveness of vaccination during COVID-19 pandemic are reviewed.The 13C-depleted methane in terrigenous shale gas: A case study in the Triassic Yanchang Formation, Ordos Basin
01 Apr 2022 - Marine and Petroleum Geology
In this paper , the authors focus on shale gas in the Yanchang Formation of the Ordos Basin and obtain the shale gas from pressure coring, and the gas desorption experiment was carried out under normal temperature and heating conditions, the core residual gas was obtained by crushing and the components and carbon isotopic composition of gas and residual gas were analyzed.A planar piezoelectric motor of two dimensional XY motions driven by one cross-shaped piezoelectric unit: A new principle.
01 Apr 2022 - Review of Scientific Instruments
In this article , a two-degree-of-freedom piezoelectric motor is presented, which is driven by a simple cross-shaped piezo unit with roughly equal pressing forces applied between the four free ends of the piezo units and the guiding plates.One dimensional ZnSe@N-doped carbon nanofibers with simple electrospinning route for superior Na/K-ion storage
01 Apr 2022 - Chinese Chemical Letters
In this article , one-dimensional [email protected] carbon nanofibers (NFs) were successfully synthesized by electrospinning and annealed without extra troublesome conditions.Quantitative Assessment of Airway Changes in Fibrotic Interstitial Lung Abnormality Patients by Chest CT According to Cumulative Cigarette Smoking
01 Apr 2022 - Tomography
Pi10, as a biomaker of quantitative CT in fibrotic ILA patients, can reveal that smoking affects airway remodeling.Knowledge, Readiness and Barriers of Street Food Hawkers to Support the Single-Use Plastic Reduction Program in Northeast Malaysia
01 Apr 2022 - International Journal of Environmental Research and Public Health
In this paper , a cross-sectional study was performed involving 440 night market food street hawkers from five districts in Kelantan, Malaysia selected through proportionate random sampling from 17 night market locations.Is a New Combined Treatment With Laser 980 nm in the Proximal GSV and Foam Sclerotherapy at the Distal GSV Useful to Treat Venous Incompetence of the Lower Extremities?
01 Apr 2022 - Journal of Vascular Surgery
In this paper , a new great saphenous vein (GSV) ablation method combining endovenous laser ablation (EVLA) for the proximal GSV segment with simultaneous foam sclerotherapy was proposed.Implant removal following open reduction and internal fixation for distal radius fracture: A study based on the Diagnosis Procedure Combination database in Japan.
01 Apr 2022 - Journal of Orthopaedic Science
In this paper , the authors retrospectively evaluated the incidence rate of implant removal in a large cohort of distal radius fracture patients obtained from the Diagnosis Procedure Combination database in Japan between April 2014 and March 2019.334 Web-based Methods for Family Health History Collection
01 Apr 2022 - Journal of clinical and translational science
KIT, an interactive chatbot to administer a family history survey in comparison to a form-based data collection tool is created to maximize rates of collection and support both patients and genetic counselors by ensuring features align with shared-decision-making frameworks.A Method for Reducing the Number of Presentations in Perimetric Test Procedures
01 Apr 2022 - Translational Vision Science & Technology
ARBON can be added to a perimetry test procedure to speed up the test while largely preserving the distribution of returned sensitivities, thus producing normative data similar to the data for the original, underlying perimetric test.Decreased serum B12 due to antidiabetic drugs: Is it a potential contributor to inflammation in Type II diabetes mellitus
01 Apr 2022 - Asian Journal of Pharmaceutical Research and Health Care
Findings from this study clearly indicates the link between decrease in B12 and progression of inflammation, and the role of metformin in vitB12 deficiency levels, uncontrolled glucose levels, and chronic inflammatory responses in T2DM patients, gradually leading to the dire consequences of B12 deficiency.The where, when, and why of surgical rib fixation: Utilization patterns, outcomes, and readmissions.
01 Apr 2022 - American Journal of Surgery
In this article , the authors analyzed statewide patterns and longer-term outcomes after surgical stabilization of rib fractures (SSRF) and found that admission to a high-volume SSRF center (SHR 4.6, CI 95 4.0-5.4, p = 0.01) was the primary predictor of SSRF.Desalojos de favelas en Río de Janeiro, Brasil: antiguo problema, nuevas justificativas
01 Apr 2022 - Scripta Nova-revista Electronica De Geografia Y Ciencias Sociales
In this article , el problem of the movilidad residencial forzada de los que viven en las favelas de la metrópoli de Río de Janeiro como reflejo de dificultades históricas de los poderes públicos for reconocer estos espacios populares como parte integrante de la ciudad.Strategy for recurrence after LT of the advanced HCC
01 Apr 2022 - International Journal of Surgery
In this article , the authors present an evaluation model to help practitioners in selecting the most suitable products for their needs in the absence of consensus on the proper use of surgical hemostatic agents.Computed tomography follow-up after elective proximal aortic surgery: less is more?
01 Apr 2022 - American Heart Journal
In this paper , the authors evaluated the benefit of CT follow-up by assessing the incidence of aorta-related complications and reinterventions detected during routine CT followup.Features of foreign tax policy in connection with the development of green technologies
01 Apr 2022 - Налоги и налогообложение
In this paper , a tax system with a negative impact on the environment is analyzed in the context of carbon regulation in the Russian Federation and the main conclusions of the tax system are determined by the specifics of the resource potential and historical aspects.中国海南岛海岸鸣沙群的发现及其意义
01 Apr 2022 - Kexue Tongbao
In this paper , the authors describe a scenario in which a large number of people are living in the vicinity of a small island in the Mediterranean Sea, namely,海岸鸣沙的分布.Recurrent Immature Teratoma
01 Apr 2022 - Journal of Pediatric and Adolescent Gynecology
In this paper , the authors present three cases of recurrent immature teratoma, which are rare ovarian malignancies and recurrences do occur, although rare, recurrence does occur.Bibliographic analysis of sustainability studies in coffee agroecosystem from 2010 to 2019
01 Apr 2022 - Agro Productividad
A systematic review of the main researches carried out on sustainability in the coffee agroecosystem and reported in the scientific literature of the last ten years is presented in this article .Percepción de la educación virtual en época de covid-19 de los estudiantes de la carrera de contaduría pública en la Universidad Nacional de Canindeyú-Paraguay, 2021
01 Apr 2022 - Ciencia latina
In this paper , an exploración of the percepción de the virtual educación virtual in the context of COVID-19 of the estudiantes of the carrera de Contaduría Pública in the Universidad Nacional de Canindeyú-Paraguay, 2019, was presented.Trends of formation and transformation of the onomastic system of the language (on the example of oikonyms)
01 Apr 2022 - Мова
In this article , the authors analyzed the reasons for linguistic changes determined by both the internal laws of language development and extralinguistic tendencies, which made it possible to conclude the unity of divergent toponymic tendencies and convergent processes of the toponyms of the language itself.From kennel maid to practice director.
01 Apr 2022 - Veterinary Record
Sophie Hadfield recently became a director of City Road Vets in Truro and is a trailblazer who encourages other members of practice teams to follow her lead.PET/CT Prediction of Head and Neck Melanoma Nodal Metastases
01 Apr 2022 - International Journal of Radiation Oncology Biology Physics
In this paper , a case series of adults who underwent lymphadenectomy for melanoma metastasis to the neck at a single tertiary academic medical center from 2000-2018 was used to determine the predictive value of PET-CT.Trending questions
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