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A. Nisalak
Researcher at Johns Hopkins University
Publications - 16
Citations - 1341
A. Nisalak is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Dengue fever & Dengue virus. The author has an hindex of 11, co-authored 16 publications receiving 1282 citations. Previous affiliations of A. Nisalak include Medical Corps.
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Journal ArticleDOI
Early Clinical and Laboratory Indicators of Acute Dengue Illness
Siripen Kalayanarooj,David W. Vaughn,S. Nimmannitya,Sharone Green,Saroj Suntayakorn,N. Kunentrasai,W. Viramitrachai,S. Ratanachu-eke,S. Kiatpolpoj,Bruce L. Innis,Alan L. Rothman,A. Nisalak,Francis A. Ennis +12 more
TL;DR: Simple clinical and laboratory parameters are identified that help to identify children with DF or DHF, including plasma AST levels were higher in children who developed DHF than in those with DF.
Journal ArticleDOI
HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais
Henry A.F. Stephens,Henry A.F. Stephens,R. Klaythong,Monchan Sirikong,D. W. Vaughn,Sharone Green,Siripen Kalayanarooj,Timothy P. Endy,Daniel H. Libraty,A. Nisalak,Bruce L. Innis,Alan L. Rothman,Francis A. Ennis,Dasnayanee Chandanayingyong +13 more
TL;DR: It is confirmed that classical HLA class I alleles are associated with the clinical outcome of exposure to dengue virus, in previously exposed and immunologically primed individuals.
Journal Article
B cells are the principal circulating mononuclear cells infected by dengue virus.
A. D. King,A. Nisalak,S. Kalayanrooj,Khin Saw Aye Myint,K. Pattanapanyasat,S. Nimmannitya,Bruce L. Innis +6 more
TL;DR: This study collected blood mononuclear cells from acutely ill dengue patients and separated the cells by flow cytometry into subsets for virus isolation, finding an equal distribution of virus between the intracellular compartment and the surface of B cells.
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Rapid Diagnosis of Dengue Viremia by Reverse Transcriptase-Polymerase Chain Reaction using 3′-Noncoding Region Universal Primers
Tjahjani Mirawati Sudiro,Hiroaki Ishiko,Sharone Green,David W. Vaughn,A. Nisalak,Siripen Kalayanarooj,Alan L. Rothman,Boonyos Raengsakulrach,Jurand Janus,Ichiro Kurane,Francis A. Ennis +10 more
TL;DR: A reverse transcriptase-polymerase chain reaction (RT-PCR) method was developed as a rapid diagnostic test of dengue viremia and could be detected in a 6-hr assay by combining a silica method for RNA isolation and RT-PCRs.
Journal ArticleDOI
Blood group AB is associated with increased risk for severe dengue disease in secondary infections.
Siripen Kalayanarooj,Robert V. Gibbons,David W. Vaughn,Sharone Green,A. Nisalak,Richard G. Jarman,Mammen P. Mammen,Guey Chuen Perng,Guey Chuen Perng +8 more
TL;DR: To the authors' knowledge, this is the first report demonstrating an association between ABO blood group and the severity of dengue disease.