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A. Paul Krapcho

Researcher at University of Vermont

Publications -  109
Citations -  1847

A. Paul Krapcho is an academic researcher from University of Vermont. The author has contributed to research in topics: Isoquinoline & Phenanthroline. The author has an hindex of 20, co-authored 109 publications receiving 1780 citations.

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Mono-Protected Diamines. N-tert-Butoxycarbonyl-α,ω-Alkanediamines from α,ω-Alkanediamines

TL;DR: In this article, the authors report a convenient pathway to N-tert-butoxycarbonyl-α,ω-alkanediamines 2a-e [H2N(CH2)χNHBOC; χ=2, 3, 4, 5 and 6; (75-90% yields) by treatment of the corresponding α,ω-,alkanedienine with di-terto-butyl dicarbonate in dioxane as the solvent.
Journal ArticleDOI

Tri-, tetra- and heptacyclic perylene analogues as new potential antineoplastic agents based on DNA telomerase inhibition

TL;DR: A series of compounds related to PIPER, a well-known perylene-based telomerase inhibitor, are synthesized, modified the number of condensed aromatic rings and introduced different side chains to modulate drug protonation state and extent of self-aggregation.