A. Rusina

Bio: A. Rusina is an academic researcher from Czechoslovak Academy of Sciences. The author has contributed to research in topics: Dimethylformamide & Phosphine. The author has an hindex of 1, co-authored 1 publications receiving 77 citations.

Formation of Rh(I)-Carbonyl Complex by the Reaction with Some Non-alcoholic, Oxygen-containing Solvents

Abstract: IT has been shown1,2 from an examination of the polarographic behaviour of some Rh(III)-arsine and phosphine complexes in dimethylformamide (DMF) as solvent that these complexes undergo reaction with the solvent. To elucidate this reaction and to identify the reaction product, an investigation has been undertaken, the results of which are reported here.

Catalytic C-C Bond Activations via Oxidative Addition to Transition Metals.

Abstract: Selective cleavages of carbon-carbon bonds catalyzed by transition-metal complexes have been shown to be increasingly versatile tools for organic synthesis allowing for complementary synthetic strategies Numerous examples of transition-metal catalyzed C-C bond activations of three- and four-membered ring systems have been reported These strained rings have been shown to engage in a variety of new ring-opening rearrangements and cycloaddition reactions leading to valuable structures Besides strain-driven transformations, other facilitating strategies to enforce the C-C bond activation of unstrained molecules have been developed as well While the variety of different transformations is less abundant, they concentrate on chelation-assisted reactions using appropriate permanent or transient directing groups In particular, the cleavage and subsequent functionalization of the C-CN bonds and decarbonylation processes operating by an excision of carbon monoxide from ketone derivatives have witnessed a large progress

Cleavage of Carbon—Carbon Single Bonds by Transition Metals

Abstract: Cleavage of carbon-carbon bonds by transition metals under homogeneous conditions has recently received much scientific and technological interest. In this review, an overview of this field is presented. The first part deals with stoichiometric reactions involving carbon-carbon bond breaking. The second part features catalytic reactions, especially those related to organic synthesis.

Potential of Metal-Catalyzed C–C Single Bond Cleavage for Organic Synthesis

Abstract: Conventional organic synthesis has been mainly based upon the reactivities of π-bonds and polar σ-bonds. Carbon–carbon single bonds are nonpolar and generally far less reactive. Although they remain intact under most reaction conditions, it is possible to activate and cleave them if suitable organometallic compounds or metal catalysts are applied. Such C–C single bond cleavage reactions are attracting increasing attention in the context of synthetic chemistry because they provide a unique and more straightforward route from readily available substances to targets, while requiring significantly fewer steps. The present Perspective aims to exemplify the potential of metal-catalyzed C–C single bond cleavage for organic synthesis.

Dimethylformamide as a carbon monoxide source in fast palladium-catalyzed aminocarbonylations of aryl bromides

Abstract: Dimethylformamide (DMF) acts as an efficient source of carbon monoxide and dimethylamine in the palladium-catalyzed aminocarbonylation (Heck carbonylation) of p-tolyl bromide to provide the dimethylamide. Addition of amines to the reaction mixture in excess delivers the corresponding aryl amides in good yields. The amines employed, benzylamine, morpholine, and aniline, all constitute good reaction partners. The reaction proceeds smoothly with bromobenzene and more electron-rich aryl bromides, but electron-deficient aryl bromides fail to undergo aminocarbonylation. The reactions are conducted at 180-190 degrees C for 15-20 min with microwave heating in a reaction mixture containing imidazole and potassium tert-butoxide: the latter is required to promote decomposition of the DMF solvent at a suitable rate. The beneficial effects of controlled microwave irradiation as an energy source for the rapid heating of the carbonylation reaction mixture are demonstrated. The carbonylation procedure reported herein, which relies on the in situ generation of carbon monoxide, serves as a convenient alternative to other carbonylation methods and is particularly applicable to small-scale reactions where short reaction times are desired and the direct use of carbon monoxide gas is impractical.