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Aarno Palotie

Researcher at University of Helsinki

Publications -  776
Citations -  108123

Aarno Palotie is an academic researcher from University of Helsinki. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 129, co-authored 711 publications receiving 89975 citations. Previous affiliations of Aarno Palotie include University of Washington & National Institutes of Health.

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Analysis of protein-coding genetic variation in 60,706 humans

Monkol Lek, +106 more
- 18 Aug 2016 - 
TL;DR: The aggregation and analysis of high-quality exome (protein-coding region) DNA sequence data for 60,706 individuals of diverse ancestries generated as part of the Exome Aggregation Consortium (ExAC) provides direct evidence for the presence of widespread mutational recurrence.
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Biological insights from 108 schizophrenia-associated genetic loci

Stephan Ripke, +354 more
- 24 Jul 2014 - 
TL;DR: Associations at DRD2 and several genes involved in glutamatergic neurotransmission highlight molecules of known and potential therapeutic relevance to schizophrenia, and are consistent with leading pathophysiological hypotheses.
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Integrating common and rare genetic variation in diverse human populations

David Altshuler, +68 more
- 02 Sep 2010 - 
TL;DR: An expanded public resource of genome variants in global populations supports deeper interrogation of genomic variation and its role in human disease, and serves as a step towards a high-resolution map of the landscape of human genetic variation.
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Discovery and refinement of loci associated with lipid levels

Cristen J. Willer, +319 more
- 06 Oct 2013 - 
TL;DR: It is found that loci associated with blood lipid levels are often associated with cardiovascular and metabolic traits, including coronary artery disease, type 2 diabetes, blood pressure, waist-hip ratio and body mass index.
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Stephen Sawcer, +265 more
- 10 Aug 2011 - 
TL;DR: In this article, a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, they have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci.