Aaron J. Courtenay

TL;DR: This review aims to concisely chart the development of two individual research fields, namely nanomedicines, with specific emphasis on nanoparticles and microparticles, and microneedle technologies, which have, in the recent past, been exploited in combinatorial approaches for the efficient delivery of a variety of medicinal agents across the skin.

TL;DR: Hydrogel-forming microneedle arrays prepared from “super swelling” polymeric compositions are described, for the first time, and may greatly expand the range of drugs that can be delivered transdermally, to the benefit of patients and industry.

TL;DR: Hydrogel‐forming microneedle (MN) patch are a promising technology that has demonstrated successful transdermal delivery of metformin HCl and potential clearly exists for administration of other high‐dose drugs using this system.

TL;DR: This review explores the chronology of microneedling methodologies, which has led to the emergence of MN devices, now extensively used in cosmeceutical applications and recent developments in therapeutic molecule and peptide delivery to the skin via MN platforms are addressed.

TL;DR: It has been demonstrated that microneedles (MNs) can increase the number of compounds amenable to transdermal delivery by penetrating the skin’s protective barrier, the stratum corneum, and creating a pathway for drug permeation to the dermal tissue below.