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Aaron Mood
Researcher at University of California, Irvine
Publications - 5
Citations - 191
Aaron Mood is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Affinities & Corpus albicans. The author has an hindex of 3, co-authored 5 publications receiving 123 citations. Previous affiliations of Aaron Mood include University of California.
Papers
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Journal ArticleDOI
Deep learning for chemical reaction prediction
David Fooshee,Aaron Mood,Eugene S. Gutman,Mohammadamin Tavakoli,Gregor Urban,Frances Liu,Nancy O Huynh,David L. Van Vranken,Pierre Baldi +8 more
TL;DR: An alternative approach to predicting electron sources and sinks using recurrent neural networks, specifically long short-term memory (LSTM) architectures, operating directly on SMILES strings is discussed, which has shown promising preliminary results.
Journal ArticleDOI
Potent Antifungal Synergy of Phthalazinone and Isoquinolones with Azoles Against Candida albicans
Aaron Mood,Ilandari Dewage Udara Anulal Premachandra,Stanley C. Hiew,Fuqiang Wang,Kevin A. Scott,Nathan J. Oldenhuis,Haoping Liu,David L. Van Vranken +7 more
TL;DR: Isoquinolone 15 and phthalazinone 24 were shown to be active against several resistant clinical isolates of C. albicans and were also shown to enhance the antifungal activity of isavuconazole, a recently FDA approved azole antIFungal.
Journal ArticleDOI
Methyl Anion Affinities of the Canonical Organic Functional Groups.
Aaron Mood,Mohammadamin Tavakoli,Eugene S. Gutman,Dora Kadish,Pierre Baldi,David L. Van Vranken +5 more
TL;DR: It is demonstrated that methyl anion affinities calculated with a solvation model (MAA*) give linear correlation with Mayr E parameters for a broad range of functional groups.
Posted Content
Quantum Mechanics and Machine Learning Synergies: Graph Attention Neural Networks to Predict Chemical Reactivity.
TL;DR: In this article, deep learning methods were used to predict the reactivity of molecular structures and train them using this curated dataset in combination with different representations of molecular structure using tenfold cross-validation.
Patent
Spiroindolinones and therapeutic uses thereof
David Lee Van Vranken,Haoping Liu,Ilandari Dewage Udara Anulal Premachandra,Fuqiang Wang,Chengtian Shen,Kevin A. Scott,Shelley Lane,Aaron Mood,Stanley C. Hiew +8 more
TL;DR: In this article, small molecules comprised of spiroindolinone analogues are provided with a particular relative stereochemistry in which the indolone carbonyl and all three hydrogens are on the same face of the central pyrrolidine ring.