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Aaron R. Dinner
Researcher at University of Chicago
Publications - 225
Citations - 18680
Aaron R. Dinner is an academic researcher from University of Chicago. The author has contributed to research in topics: Umbrella sampling & Cytoskeleton. The author has an hindex of 49, co-authored 211 publications receiving 15982 citations. Previous affiliations of Aaron R. Dinner include New York University & Harvard University.
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Journal ArticleDOI
CHARMM: the biomolecular simulation program.
Bernard R. Brooks,Charles L. Brooks,Alexander D. MacKerell,Lennart Nilsson,Robert J. Petrella,Benoît Roux,Youngdo Won,Georgios Archontis,Christian Bartels,Stefan Boresch,Amedeo Caflisch,Leo S. D. Caves,Qiang Cui,Aaron R. Dinner,Michael Feig,Stefan Fischer,Jiali Gao,Milan Hodošček,Wonpil Im,K. Kuczera,Themis Lazaridis,Jianpeng Ma,V. Ovchinnikov,Emanuele Paci,Richard W. Pastor,Carol Beth Post,Jingzhi Pu,M. Schaefer,Bruce Tidor,Richard M. Venable,H. L. Woodcock,Xiongwu Wu,Wei Yang,Darrin M. York,Martin Karplus,Martin Karplus +35 more
TL;DR: An overview of the CHARMM program as it exists today is provided with an emphasis on developments since the publication of the original CHARMM article in 1983.
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Multilineage Transcriptional Priming and Determination of Alternate Hematopoietic Cell Fates
Peter Laslo,Chauncey J. Spooner,Aryeh Warmflash,David W. Lancki,Hyun Jun Lee,Roger Sciammas,Benjamin N. Gantner,Aaron R. Dinner,Harinder Singh +8 more
TL;DR: It is demonstrated that at subthreshold levels, this Ets transcription factor regulates a mixed pattern (macrophage/neutrophil) of gene expression within individual myeloid progenitors, and assembled and mathematically model a gene regulatory network that exhibits both graded and bistable behaviors.
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Effects of diurnal variation of gut microbes and high-fat feeding on host circadian clock function and metabolism.
Vanessa Leone,Sean M. Gibbons,Sean M. Gibbons,Kristina Martinez,Alan L. Hutchison,Edmond Y. Huang,Candace M. Cham,Joseph F. Pierre,Aaron F. Heneghan,Anuradha Nadimpalli,Nathaniel Hubert,Elizabeth Zale,Yunwei Wang,Yong Huang,Betty Theriault,Aaron R. Dinner,Mark W. Musch,Kenneth A. Kudsk,Brian J. Prendergast,Jack A. Gilbert,Jack A. Gilbert,Eugene B. Chang +21 more
TL;DR: The ability of microbially derived metabolites to regulate or modify central and hepatic circadian rhythm and host metabolic function, the latter following intake of a Westernized diet is underscored.
Journal ArticleDOI
The immunological synapse balances T cell receptor signaling and degradation.
Kyeong-Hee Lee,Kyeong-Hee Lee,Aaron R. Dinner,Chun Tu,Gabriele Campi,Subhadip Raychaudhuri,Rajat Varma,Tasha N. Sims,W. Richard Burack,Hui Wu,Julia Wang,Osami Kanagawa,Mary A. Markiewicz,Paul M. Allen,Michael L. Dustin,Arup K. Chakraborty,Arup K. Chakraborty,Andrey S. Shaw +17 more
TL;DR: In vitro and in silico experiments are used to determine that the immunological synapse acts as a type of adaptive controller that both boosts T cell receptor triggering and attenuates strong signals.
Journal ArticleDOI
Understanding protein folding via free-energy surfaces from theory and experiment
TL;DR: The ability of protein molecules to fold into their highly structured functional states is one of the most remarkable evolutionary achievements of biology and the development of energy surfaces, which allow the folding reaction to be described and visualized in a meaningful manner, is studied.