Abba C. Zubair

TL;DR: Results indicate that mIL‐6‐mediated reactive gliosis may be beneficial early in the disease process by potentially enhancing Aβ plaque clearance rather than mediating a neurotoxic feedback loop that exacerbates amyloid pathology.

TL;DR: Genome-wide analysis of a multi-incident family with autosomal-dominant parkinsonism has implicated a locus on chromosomal region 3q26-q28 and highlighted a convergent pathway for monogenic, toxin and perhaps virally-induced Parkinson disease.

TL;DR: Early results show that BMAC is safe to use and is a reliable and viable cellular product and study patients experienced a similar relief of pain in both BMAC- and saline-treated arthritic knees.

TL;DR: The gene expression signature discovered in this study may represent a true "CNS signature" because it contrasted PCNSL with wide-spectrum non-CNS DLBCL on a genomic scale and performed an in-depth bioinformatic analysis.

TL;DR: Tumour cell–derived EVs can contribute to the generation of tumour stroma through fibroblastic differentiation of MSCs, and can also selectively modulate the cellular release of soluble factors such as IL-6 by M SCs that can, in turn, alter tumour cell proliferation.