Abel Sánchez-Aguilera

TL;DR: Older monozygous twins exhibited remarkable differences in their overall content and genomic distribution of 5-methylcytosine DNA and histone acetylation, affecting their gene-expression portrait, indicating how an appreciation of epigenetics is missing from the understanding of how different phenotypes can be originated from the same genotype.

TL;DR: The current knowledge of the alterations in each of these pathways is discussed, with special emphasis on the deregulation of cell cycle progression, in an attempt to integrate the available information within a global model that describes the contribution of these molecular changes to the genesis and progression of B-cell lymphomas.

TL;DR: The results suggest that EMT-related genes contribute to the promotion of the metastatic phenotype in primary CMM by supporting specific adhesive, invasive, and migratory properties.

TL;DR: Genes related to tumor microenvironment, cell growth/apoptosis, and regulation of mitosis are associated with treatment response and outcome of patients with HL.

TL;DR: Characterizing this tumor more comprehensively, and of identifying new diagnostic and prognostic markers, cDNA microarray expression profiling and tissue microarray immunohistochemical studies in a relatively large series of 44 SMZLs revealed a largely homogenous signature, implying the existence of a single molecular entity.