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Abigail A. Lamikanra
Researcher at University of Oxford
Publications - 21
Citations - 594
Abigail A. Lamikanra is an academic researcher from University of Oxford. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 13 publications receiving 468 citations. Previous affiliations of Abigail A. Lamikanra include John Radcliffe Hospital & NHS Blood and Transplant.
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Journal ArticleDOI
Malarial anemia: of mice and men.
Abigail A. Lamikanra,Douglas E. Brown,Alexandre J. Potocnik,Climent Casals-Pascual,Climent Casals-Pascual,Jean Langhorne,David J. Roberts +6 more
TL;DR: The recent clinical and experimental studies of malaria are summarized to highlight similarities and differences in human and mouse pathology that result in anemia and so inform the use of mouse models in the study of severe malarial anemia in humans.
Journal ArticleDOI
Hemozoin (malarial pigment) directly promotes apoptosis of erythroid precursors.
TL;DR: In an in vitro model of erythropoiesis, inhibition of ERYthroid cell development by hemozoin isolated from P. falciparum is shown, consistent with a direct effect of hemozosin in inducing apoptosis in developing erythroid cells in malarial anemia.
Journal ArticleDOI
The role of vitamin D in increasing circulating T regulatory cell numbers and modulating T regulatory cell phenotypes in patients with inflammatory disease or in healthy volunteers: A systematic review
Sheila A Fisher,Sheila A Fisher,Mana Rahimzadeh,Charlotte K. Brierley,Betty Gration,Carolyn Doree,Carolyn Doree,Catherine E. Kimber,Catherine E. Kimber,Alicia Plaza Cajide,Alicia Plaza Cajide,Abigail A. Lamikanra,Abigail A. Lamikanra,David J. Roberts,David J. Roberts,David J. Roberts +15 more
TL;DR: Vitamin D supplementation may increase Treg/CD3 ratios in both healthy individuals and patients with autoimmune disorders and may increase the proportion of Tregs in patients with inflammatory or autoimmune disease.
Journal ArticleDOI
Increased regulatory T cell graft content is associated with improved outcome in haematopoietic stem cell transplantation: a systematic review
Sheila A Fisher,Sheila A Fisher,Abigail A. Lamikanra,Abigail A. Lamikanra,Carolyn Doree,Carolyn Doree,Betty Gration,Pat Tsang,Pat Tsang,Robert Danby,David J. Roberts,David J. Roberts,David J. Roberts +12 more
TL;DR: In this paper, a systematic review of studies that reported the Treg composition of HSCT grafts in patients with haematological malignancies was conducted, with a significant reduction in non-relapse mortality and a reduced risk of acute graft-versus-host disease (GVHD).
Journal ArticleDOI
Interleukin-10 regulates hepcidin in Plasmodium falciparum malaria.
Honglei Huang,Abigail A. Lamikanra,Matthew S. Alkaitis,Marie L. Thézénas,Abhinay Ramaprasad,Ehab M. Moussa,Ehab M. Moussa,David J. Roberts,Climent Casals-Pascual +8 more
TL;DR: IL-10 can directly regulate hepcidin in primary macrophages but not in HepG2 cells, consistent with a role for IL-10 in modulating iron metabolism during acute phase of infection.