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Abolfazl Jahangiri
Researcher at Baqiyatallah University of Medical Sciences
Publications - 56
Citations - 924
Abolfazl Jahangiri is an academic researcher from Baqiyatallah University of Medical Sciences. The author has contributed to research in topics: Acinetobacter baumannii & Medicine. The author has an hindex of 16, co-authored 40 publications receiving 549 citations. Previous affiliations of Abolfazl Jahangiri include Shahed University.
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In silico design of an immunogen against Acinetobacter baumannii based on a novel model for native structure of Outer membrane protein A
TL;DR: A novel immunogen with lower toxicity and higher antigenicity was designed based on structural vaccinology and could trigger antibodies rendering protection against two important nosocomial pathogens i.e. Pseudomonas aeruginosa and A. baumannii.
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Antimicrobial peptides as a promising treatment option against Acinetobacter baumannii infections.
Alireza Neshani,Hamid Sedighian,Seyed Ali Mirhosseini,Kiarash Ghazvini,Hosna Zare,Abolfazl Jahangiri +5 more
TL;DR: Evidence from this review indicates that AMPs would be likely among the main anti-A.
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Computational vaccinology and epitope vaccine design by immunoinformatics
TL;DR: Advances in genomics and vaccine design and their relevance to the development of effective vaccines are discussed furthermore several division of this field and available tools in each item are introduced.
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An in silico DNA vaccine against Listeria monocytogenes.
Abolfazl Jahangiri,Iraj Rasooli,Seyed Latif Mousavi Gargari,Parviz Owlia,Mohammad Rahbar,Jafar Amani,Saeed Khalili +6 more
TL;DR: MRNAs from optimized DNA sequences of both human and mouse constructs are more stable than the native and are suitable for initiation of translation, and contain several sites for phosphorylation that could improve its degradation and subsequent entry into the MHC class I pathway.
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Specific egg yolk antibodies (IgY) confer protection against Acinetobacter baumannii in a murine pneumonia model.
Abolfazl Jahangiri,Abolfazl Jahangiri,Parviz Owlia,Iraj Rasooli,Jafar Salimian,E. Derakhshanifar,A. Naghipour Erami,E. Darzi Eslam,S H Darvish Alipour Astaneh +8 more
TL;DR: In this article, the antigenicity of two recombinant outer membrane proteins (OmpA and Omp34) as well as inactivated whole cell of A. baumannii was assessed by ELISA and the specific IgY antibodies had various prophylactic effects in the pneumonia model.