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Abraham Mayevsky

Bio: Abraham Mayevsky is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Sperm motility & Sperm. The author has an hindex of 2, co-authored 2 publications receiving 86 citations.

Papers
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Journal ArticleDOI
TL;DR: The sperm motility index provides a reliable and objective reflection of semen motility parameters and quality and represents semen quality assessment obtained by two experienced andrologists.

68 citations

Patent
22 May 1978
TL;DR: In this article, a method and apparatus for measuring sperm motility is described in which a suspension of the sperm cells is placed in a transparent container, and a predetermined field of the specimen is continuously examined by photoelectric means for detecting variations in optical density caused by the collective wave-like motion of batches of the cells through the examined field.
Abstract: A method and apparatus for measuring sperm motility are described in which a suspension of the sperm cells is placed in a transparent container, and a predetermined field of the specimen is continuously examined by photoelectric means for detecting variations in optical density caused by the collective wave-like motion of batches of the sperm cells through the examined field. An amplitude-modulated analog electrical signal is generated by the photoelectric means in response to the variations in optical density, and the peaks and valleys of this signal are counted over a predetermined time period to provide an index of sperm motility. This technique may be, and preferably is, performed on undiluted sperm suspensions as taken from the sperm-producing organism. In addition, it may be performed quickly, is non-destructive, and provides an objective index of motility which has been found to closely correlate with actual results.

20 citations


Cited by
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Journal ArticleDOI
TL;DR: For the first time, incorporation of labeled amino acids into polypeptides during sperm capacitation is demonstrated, which was completely inhibited by mitochondrial translation inhibitors but not by the cytoplasmic translation inhibitor.
Abstract: It is widely accepted that spermatozoa are translationally silent. The present study demonstrates, for the first time, incorporation of labeled amino acids into polypeptides during sperm capacitation, which was completely inhibited by mitochondrial translation inhibitors but not by the cytoplasmic translation inhibitor. Unlike 80S cytoplasmic ribosomes, 55S mitochondrial ribosomes were present in polysomal fractions, indicating that these ribosomes are actively involved in protein translation in spermatozoa. Inhibition of protein translation significantly reduced sperm motility, capacitation and in vitro fertilization rate. Thus, contrary to the accepted dogma, nuclear genes are expressed as proteins in sperm during their residence in the female reproductive tract until fertilization.

322 citations

Patent
21 Jan 1994
TL;DR: In this paper, a sperm sample is applied to the inlet port, and the sperm in the sample are permitted to competitively migrate from the sample through the channel to the egg nesting chamber, where in vitro fertilization occurs.
Abstract: Devices and methods are provided for the clinical analysis of a sperm sample. The devices include a solid substrate, typically on the order of a few millimeters thick and approximately 0.2 to 2.0 centimeters square, microfabricated to define a sample inlet port and a mesoscale flow channel extending from the inlet port. In one embodiment, a sperm sample is applied to the inlet port, and the competitive migration of the sperm sample through the mesoscale flow channel is detected to serve as an indicator of sperm motility. In another embodiment, the substrate of the device is microfabricated with a sperm inlet port, an egg nesting chamber, and an elongate mesoscale flow channel communicating between the egg nesting chamber and the inlet port. In this embodiment, a sperm sample is applied to the inlet port, and the sperm in the sample are permitted to competitively migrate from the inlet port through the channel to the egg nesting chamber, where in vitro fertilization occurs. The devices of the invention may be used in a wide range of applications in the analysis of a sperm sample, including the analysis of sperm morphology or motility, to assess sperm binding properties, and for in vitro fertilization.

315 citations

Journal ArticleDOI
TL;DR: Analysis of specific sperm swelling patterns showed that those patterns considered to reflect maximal sperm swelling were indicative of high fertility, and correlation coefficients among the various sperm characteristics and fertility of bulls were highly significant.

212 citations

Journal ArticleDOI
01 Feb 2004-Genetics
TL;DR: It is revealed that incompatibility of interactions of X-linked gene(s) with autosomal and/or Y-linked genes causes the hybrid breakdown between the genetically distant C57BL/6J and MSM/Ms strains.
Abstract: Hybrid breakdown is a type of reproductive failure that appears after the F2 generation of crosses between different species or subspecies. It is caused by incompatibility between interacting genes. Genetic analysis of hybrid breakdown, particularly in higher animals, has been hampered by its complex nature (i.e., it involves more than two genes, and the phenotype is recessive). We studied hybrid breakdown using a new consomic strain, C57BL/6J-X(MSM), in which the X chromosome of C57BL/6J (derived mostly from Mus musculus domesticus) is substituted by the X chromosome of the MSM/Ms strain (M. m. molossinus). Males of this consomic strain are sterile, whereas F1 hybrids between C57BL/6J and MSM/Ms are completely fertile. The C57BL/6J-X(MSM) males showed reduced testis weight with variable defects in spermatogenesis and abnormal sperm head morphology. We conducted quantitative trait locus (QTL) analysis for these traits to map the X-linked genetic factors responsible for the sterility. This analysis successfully detected at least three distinct loci for the sperm head morphology and one for the testis weight. This study revealed that incompatibility of interactions of X-linked gene(s) with autosomal and/or Y-linked gene(s) causes the hybrid breakdown between the genetically distant C57BL/6J and MSM/Ms strains.

130 citations

Journal ArticleDOI
TL;DR: Diluting dog semen samples to 50 x 10(6) ml(-1) with physiological saline solution and scanning 30 frames at a frame rate of 60 frames/s are the set-up parameters proposed to obtain objective and standardized canine semen motility results using the HTR Ceros 12.1.

116 citations