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Adam J. Reid
Researcher at Wellcome Trust Sanger Institute
Publications - 69
Citations - 3695
Adam J. Reid is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Malaria & Genome. The author has an hindex of 26, co-authored 60 publications receiving 2981 citations. Previous affiliations of Adam J. Reid include Wellcome Trust & University College London.
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Journal ArticleDOI
Genomic insights into the origin of parasitism in the emerging plant pathogen Bursaphelenchus xylophilus.
Taisei Kikuchi,James Cotton,Jonathan J. Dalzell,Koichi Hasegawa,Natsumi Kanzaki,Paul McVeigh,Takuma Takanashi,Isheng J. Tsai,Samuel Assefa,Peter J. A. Cock,Thomas D. Otto,Martin Hunt,Adam J. Reid,Alejandro Sanchez-Flores,Kazuko Tsuchihara,Toshiro Yokoi,Mattias C. Larsson,Mattias C. Larsson,Johji Miwa,Aaron G. Maule,Norio Sahashi,John T. Jones,Matthew Berriman +22 more
TL;DR: A high-quality draft genome sequence from an inbred line of B. xylophilus is presented, and the lack of proteins homologous to effectors from other plant parasitic nematodes confirms the distinctive molecular basis of plant parasitism in the Bursaphelenchus lineage.
Journal ArticleDOI
The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery
Roz Laing,Taisei Kikuchi,Taisei Kikuchi,Axel Martinelli,Isheng J. Tsai,Isheng J. Tsai,Robin N. Beech,Elizabeth Redman,Nancy Holroyd,David J. Bartley,Helen Beasley,Collette Britton,David M. Curran,Eileen Devaney,Aude Gilabert,Martin Hunt,Frank Jackson,Stephanie L Johnston,Ivan Kryukov,Keyu Li,Alison A. Morrison,Adam J. Reid,Neil Sargison,Gary Saunders,Gary Saunders,James D. Wasmuth,Adrian J. Wolstenholme,Matthew Berriman,John S. Gilleard,James Cotton +29 more
TL;DR: The H. contortus genome and transcriptome provide an essential platform for postgenomic research in this and other important strongylid parasites and provide the most comprehensive understanding yet of the action of several important anthelmintics.
Journal ArticleDOI
The CATH domain structure database: new protocols and classification levels give a more comprehensive resource for exploring evolution.
Lesley H. Greene,Tony E. Lewis,Sarah Addou,Alison L. Cuff,Timothy J. Dallman,Mark Dibley,Oliver C. Redfern,Frances M. G. Pearl,Rekha Nambudiry,Adam J. Reid,Ian Sillitoe,Corin Yeats,Janet M. Thornton,Christine A. Orengo +13 more
TL;DR: There has been a 20% increase in the number of structural domains classified in CATH, up to 86 151 domains, and an update of the CATH Dictionary of homologous structures (CATH-DHS) which now contains multiple structural alignments, consensus information and functional annotations for 1459 well populated superfamilies in Cath.
Journal ArticleDOI
The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode
James Cotton,Catherine J. Lilley,Laura M. Jones,Taisei Kikuchi,Adam J. Reid,Peter Thorpe,Peter Thorpe,Isheng J. Tsai,Isheng J. Tsai,Isheng J. Tsai,Helen Beasley,Vivian C. Blok,Peter J. A. Cock,Sebastian Eves-van den Akker,Sebastian Eves-van den Akker,Nancy Holroyd,Martin Hunt,Sophie Mantelin,Hardeep Naghra,Hardeep Naghra,Arnab Pain,Arnab Pain,Juan E. Palomares-Rius,Juan E. Palomares-Rius,Magdalena Zarowiecki,Matthew Berriman,John T. Jones,Peter E. Urwin +27 more
TL;DR: The complete genome sequence of G. pallida is presented, together with transcriptomic data from most of the nematode life cycle, particularly focusing on the life cycle stages involved in root invasion and establishment of the biotrophic feeding site.
Journal ArticleDOI
Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy
Adam J. Reid,Sarah J. Vermont,James Cotton,David Harris,Grant A. Hill-Cawthorne,Stephanie Könen-Waisman,Sophia M. Latham,Tobias Mourier,Rebecca Norton,Michael A. Quail,Mandy Sanders,Dhanasekaran Shanmugam,Amandeep Sohal,James D. Wasmuth,James D. Wasmuth,Brian P. Brunk,Michael E. Grigg,Jonathan C. Howard,John Parkinson,David S. Roos,Alexander J. Trees,Matthew Berriman,Arnab Pain,Arnab Pain,Jonathan M. Wastling +24 more
TL;DR: The ecological niches occupied by these species are influenced by a relatively small number of gene products which operate at the host-parasite interface and that the dominance of vertical transmission in N. caninum may be associated with the evolution of reduced virulence in this species.