A
Adrian C. Newland
Researcher at Queen Mary University of London
Publications - 315
Citations - 14426
Adrian C. Newland is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Apoptosis & Romiplostim. The author has an hindex of 58, co-authored 309 publications receiving 13575 citations. Previous affiliations of Adrian C. Newland include University of Rome Tor Vergata & St Bartholomew's Hospital.
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Journal ArticleDOI
International consensus report on the investigation and management of primary immune thrombocytopenia.
Drew Provan,Roberto Stasi,Adrian C. Newland,Victor S. Blanchette,Paula H. B. Bolton-Maggs,James B. Bussel,Beng H. Chong,Douglas B. Cines,Terry Gernsheimer,Bertrand Godeau,John D. Grainger,Ian A. Greer,Beverley J. Hunt,Paul Imbach,Gordon Lyons,Robert McMillan,Francesco Rodeghiero,Miguel A. Sanz,Michael D. Tarantino,Shirley Watson,Joan Young,David J. Kuter +21 more
TL;DR: This consensus document aims to report on new data and provide consensus-based recommendations relating to diagnosis and treatment of ITP in adults, in children, and during pregnancy.
Journal ArticleDOI
Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial
David J. Kuter,James B. Bussel,Roger M. Lyons,Vinod Pullarkat,Terry Gernsheimer,Francis M. Senecal,Louis M. Aledort,James N. George,Craig M. Kessler,Miguel A. Sanz,Howard A. Liebman,Frank T. Slovick,J. Th. M. de Wolf,Emmanuelle Bourgeois,Troy H. Guthrie,Adrian C. Newland,Jeffrey S. Wasser,Solomon I. Hamburg,Carlos Grande,François Lefrère,Alan E. Lichtin,Michael D. Tarantino,Howard R. Terebelo,Jean François Viallard,Francis J. Cuevas,Ronald S. Go,David H. Henry,Robert L. Redner,Lawrence Rice,Martin R. Schipperus,D. Matthew Guo,Janet L. Nichol +31 more
TL;DR: Romiplostim was well tolerated, and increased and maintained platelet counts in splenectomised and non-splenECTomised patients with ITP and treatment safety was good.
Journal Article
Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy
Drew Provan,Adrian C. Newland,D Norfolk,Paula H B Bolton-Maggs,J Lilleyman,Ian A. Greer,A May,Michael F. Murphy,Willem H. Ouwehand,Shirley Watson,Haematology Bcs. +10 more
TL;DR: This guideline aims to assess available diagnostic tests and therapies, and attempts to provide a rational approach to the diagnosis and treatment in adults, children and in pregnancy.
Journal ArticleDOI
Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura: a systematic review
Roberto Stasi,Ameet Sarpatwari,Jodi B Segal,John Osborn,Maria Laura Evangelista,Nichola Cooper,Drew Provan,Adrian C. Newland,Sergio Amadori,James B. Bussel +9 more
TL;DR: The detection and eradication of H pylori infection should be considered in the work-up of patients with seemingly typical ITP, and the response rate tended to be higher in countries with a high background prevalence of Hpylori infections and in patients with milder degrees of thrombocytopenia.
Journal ArticleDOI
Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells.
TL;DR: It is proposed that the early stages of autophagy are required for, but do not necessarily result in, TNFα‐induced apoptosis.