scispace - formally typeset
A

Adrienne M. Gorman

Researcher at National University of Ireland, Galway

Publications -  100
Citations -  17171

Adrienne M. Gorman is an academic researcher from National University of Ireland, Galway. The author has contributed to research in topics: Unfolded protein response & Apoptosis. The author has an hindex of 42, co-authored 96 publications receiving 14790 citations. Previous affiliations of Adrienne M. Gorman include Karolinska Institutet & University of St Andrews.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Mediators of endoplasmic reticulum stress-induced apoptosis.

Eva Szegezdi, +3 more
- 01 Sep 2006 - 
TL;DR: The role of the molecules that are activated during the UPR is examined in order to identify the molecular switch from the adaptive phase to apoptosis and how the activation of these molecules leads to the commitment of death and the mechanisms that are responsible for the final demise of the cell.
Journal ArticleDOI

The integrated stress response.

Karolina Pakos-Zebrucka, +5 more
- 01 Oct 2016 - 
TL;DR: Current understanding of the ISR signaling is reviewed and how it regulates cell fate under diverse types of stress is reviewed.
Journal ArticleDOI

Cellular Stress Responses: Cell Survival and Cell Death

Simone Fulda, +3 more
- 21 Feb 2010 - 
TL;DR: The implications of cellular stress responses to human physiology and diseases are manifold and will be discussed in this review in the context of some major world health issues such as diabetes, Parkinson's disease, myocardial infarction, and cancer.
Journal ArticleDOI

The eIF2α kinases: their structures and functions

Neysan Donnelly, +3 more
- 26 Jan 2013 - 
TL;DR: While significant sequence similarity exists between the eIF2α kinases in their kinase domains, underlying their common role in phosphorylating eif2α, additional unique features determine the regulation of these four proteins, that is, what signals activate them.