Agnieszka Galanty

TL;DR: The correlations between the structure and the cytotoxicity of both steroid and triterpenoid saponins have been described as well as the most common mechanisms of action.

TL;DR: In this article, the authors focused on the comparison of the biological and pharmacological activities of usnic acid enantiomers and paid special attention to the experiments comparing both (+)- and (−)-usnic acid at the same time, which indicated interesting differences, however no tendency as to which enantiomer was more potent could be observed.

TL;DR: The ability of usnic acid and atranorin to inhibit cancer cells motility may have future implications for development of new therapeutic strategies targeted at the interference with the metastatic cascade.

TL;DR: Atranorin seems to be an interesting lichen substance, which needs to be investigated in more detail in order to allow further applications, e.g. in pharmacy, medicine or cosmetology.

TL;DR: The inhibition of cancer cell proliferation, the induction of apoptosis and attenuation of cell invasiveness is observed in the presence of low saponin concentrations, which illustrates the relationships between the action of saponins, and the momentary genomic/proteomic status of cancer cells.