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Ai Marumo

Bio: Ai Marumo is an academic researcher from Toho University. The author has contributed to research in topics: Licochalcone A & Methicillin-resistant Staphylococcus aureus. The author has an hindex of 2, co-authored 2 publications receiving 462 citations.

Papers
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Journal ArticleDOI
TL;DR: Three new isoflavonoids with a pyran ring, gancaonols A[bond]C, were isolated together with 15 known flavonoids and exhibited anti-H.

352 citations

Journal ArticleDOI
TL;DR: Nineteen flavonoids isolated from licorice were tested for their antimicrobial activities against methicillin sensitive Staphylococcus aureus, methamphetamineicillin resistant S. aureUS, Micrococcus luteus, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa.

153 citations


Cited by
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Journal ArticleDOI
TL;DR: This review summarizes the phytochemical, pharmacological and pharmacokinetics data, together with the clinical and adverse effects of licorice and its bioactive components.
Abstract: The roots and rhizomes of licorice (Glycyrrhiza) species have long been used worldwide as a herbal medicine and natural sweetener. Licorice root is a traditional medicine used mainly for the treatment of peptic ulcer, hepatitis C, and pulmonary and skin diseases, although clinical and experimental studies suggest that it has several other useful pharmacological properties such as antiinflammatory, antiviral, antimicrobial, antioxidative, anticancer activities, immunomodulatory, hepatoprotective and cardioprotective effects. A large number of components have been isolated from licorice, including triterpene saponins, flavonoids, isoflavonoids and chalcones, with glycyrrhizic acid normally being considered to be the main biologically active component. This review summarizes the phytochemical, pharmacological and pharmacokinetics data, together with the clinical and adverse effects of licorice and its bioactive components.

1,053 citations

Journal ArticleDOI
Wenying Ren1, Zhenhua Qiao1, Hong-wei Wang1, Lei Zhu1, Li Zhang1 
TL;DR: Results from laboratory studies, epidemiological investigations, and human clinical trials indicate that flavonoids have important effects on cancer chemoprevention and chemotherapy.
Abstract: Flavonoids are polyphenolic compounds that are ubiquitously in plants. They have been shown to possess a variety of biological activities at nontoxic concentrations in organisms. The role of dietary flavonoids in cancer prevention is widely discussed. Compelling data from laboratory studies, epidemiological investigations, and human clinical trials indicate that flavonoids have important effects on cancer chemoprevention and chemotherapy. Many mechanisms of action have been identified, including carcinogen inactivation, antiproliferation, cell cycle arrest, induction of apoptosis and differentiation, inhibition of angiogenesis, antioxidation and reversal of multidrug resistance or a combination of these mechanisms. Based on these results, flavonoids may be promising anticancer agents.

1,005 citations

Journal ArticleDOI
TL;DR: This review is complementary to earlier reviews and covers more recent reports of antimicrobial activity of chalcones (antibacterial and antifungal), as well as antileishmanial, antimalarial, antiviral and anti-inflammatory activities of these compounds.

956 citations

Journal ArticleDOI
TL;DR: The activities described here show that there are many potential new classes of anti-staphylococcal agents which should undergo further cytotoxicity, microbial specificity and preclinical in vivo studies to assess their potential.

495 citations

Journal ArticleDOI
TL;DR: This review describes the progress in chemical analysis of licorice and its preparations since 2000, and concludes that the combination of HPLC and LC/MS is currently the most powerful technique for the quality control of Licorice.

466 citations