Akshay Joshi

TL;DR: The developed Alginate-Gelatin based 3D scaffold maintains the required balance between biomechanics and soft tissue regeneration and improves mechanical properties by matrix secretion.

TL;DR: This research utilizes the exogenous and endogenous GFs sequestering capability of heparin functionalized PCL/gelatin co-spun nanofabrics to mediate synergistically driven tissue regeneration by utilizing combined therapeutic effect of exogenous, endogenous and endogenousGFs, and thereby minimizing the sole dependency on exogenous GFs for tissue regeneration.

TL;DR: A hybrid system to encapsulate CPT inside the amphiphilic micelle and coat it with RBC membrane is developed, which resulted in the increased overall survival of mice treated with the nano formulation and showed strong retention inside the Ehrlich Ascites Carcinoma mice models for at least 72 h, suggesting camouflaging ability conferred by RBC membranes.

TL;DR: A balance between antibacterial activity and cytocompatibility was found at optimum brush length achieved after 18 h of SIATRP suggesting that this composition offers a stable, non-leaching, anti-infective, but cytoc Compatible coating on biodegradable polymeric implant surface for addressing several biomaterials associated infections.

TL;DR: The Review concludes with the current limitations and future directions that can help 3D printing emerge as an effective biofabrication technique to realize tissues with physiologically relevant vasculatures to ultimately accelerate clinical translation.