A
Alan Morrison
Researcher at University of Chicago
Publications - 4
Citations - 349
Alan Morrison is an academic researcher from University of Chicago. The author has contributed to research in topics: DNA gyrase & Circular bacterial chromosome. The author has an hindex of 4, co-authored 4 publications receiving 344 citations.
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Journal ArticleDOI
Site-specific cleavage of DNA by E. coli DNA gyrase.
TL;DR: Analysis of cleavage fragments showed that cutting between a TG doublet is common to most, or all, gyrase cleavages, and this diverse recognition sequence with common elements is a pattern shared with several other specific nucleic acid-protein interactions.
Journal ArticleDOI
Interaction between DNA gyrase and its cleavage site on DNA.
TL;DR: It is concluded that gyrase remains stationarily bound at the discrete locations where it cleaves the DNA and that ATP changes the conformational state of the enzyme, thus altering the proportion of bound gyrases that cleaves.
Journal ArticleDOI
Structure and activities of Escherichia coli DNA gyrase.
Craig L. Peebles,N P Higgins,Kenneth N. Kreuzer,Alan Morrison,Patrick O. Brown,Akio Sugino,Nicholas R. Cozzarelli +6 more
Book ChapterDOI
Mechanisms of dna topoisomerases
Alan Morrison,Patrick O. Brown,Kenneth N. Kreuzer,Richard Otter,Stephen P. Gerrard,Nicholas R. Cozzarelli +5 more
TL;DR: The ability of E. coli omega protein to catenate duplex DNA rings suggests a unified mechanism for topoisomerases, analogous to the action of gyrase on double-stranded DNA.