Alasdair Ivens

TL;DR: Nahrendorf et al. as discussed by the authors explored the possibility that protection from severe malaria is a form of tolerance - the body learns to limit the damage the infection causes - by switching off damaging inflammation.

TL;DR: It is shown that a single malaria episode is sufficient to induce host adaptations that can minimise inflammation, prevent tissue damage and avert endothelium activation, a hallmark of severe disease.

TL;DR: It is suggested that gravid adult female worms secrete the largest diversity of extracellular sRNAs compared to adult males or microfilariae, and differences in the parasite sRNA biotype distribution detected in vitro versus in vivo are shown.

TL;DR: In this paper, the authors explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, asking whether this relationship underpins the variation observed in controlled human malaria infection (CHMI).

TL;DR: In this article, the authors analyzed the native substrate profile of AcrB in Escherichia coli MG1655 and Salmonella enterica serovar Typhimurium SL1344 using an untargeted metabolomics approach.