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Alba Chimirri

Researcher at University of Messina

Publications -  63
Citations -  1033

Alba Chimirri is an academic researcher from University of Messina. The author has contributed to research in topics: Anticonvulsant Agent & Bicyclic molecule. The author has an hindex of 17, co-authored 63 publications receiving 987 citations. Previous affiliations of Alba Chimirri include University of Perugia & Magna Græcia University.

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5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice

TL;DR: In this paper, a series of 3 a,4-dihydro-5 H -1,2,4]oxadiazolo[5,4- d ][1,5]benzothiazepines have been synthesized by 1,3-dipolar cycloaddition reaction of benzonitriloxide to the C N double bond of 1,5-benzosine derivatives, and the stereochemical features of compounds obtained have been determined by NMR spectroscopy.
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Synthesis and anti-hIV activity of 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole structurally-related 1,2-substituted benzimidazoles.

TL;DR: The synthesis of 1,2-substituted benzimidazoles is reported, which were found to be less potent than 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4-a]benzimidrazole (TBZ).
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1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: novel AMPA receptor antagonists.

TL;DR: The synthesis of new 1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones and the evaluation of their anticonvulsant effects are described and the observed findings extend the structure-activity relationships previously suggested for this class of anticonVulsants.
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Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-(thi)one derivatives

TL;DR: The results of the in vitro tests showed that some of the 2,3-diaryl-1, 3-thiazolidine-4-thione derivatives proved to be effective inhibitors of HIV-1 replication.
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Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains.

TL;DR: The rational discovery of N(1)-arylsulfonyl-1,3-dihydro-2H-benzimidazol-2-one as a novel template for the design of new non-nucleoside reverse transcriptase inhibitors (NNRTIs) that are active against wild-type and mutant strains of HIV-1 was found.