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Alban Lermine
Researcher at Curie Institute
Publications - 14
Citations - 617
Alban Lermine is an academic researcher from Curie Institute. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 6, co-authored 9 publications receiving 461 citations. Previous affiliations of Alban Lermine include French Institute of Health and Medical Research & PSL Research University.
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Journal ArticleDOI
Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries
Valentina Boeva,Valentina Boeva,Caroline Louis-Brennetot,Agathe Peltier,Simon Durand,Cécile Pierre-Eugène,Virginie Raynal,Virginie Raynal,Heather C. Etchevers,Sophie Thomas,Alban Lermine,Estelle Daudigeos-Dubus,Birgit Geoerger,Martin F. Orth,Thomas G. P. Grunewald,Elise Diaz,Elise Diaz,Bertrand Ducos,Bertrand Ducos,Bertrand Ducos,Didier Surdez,Angel M. Carcaboso,Irina V. Medvedeva,Thomas Deller,Valérie Combaret,Eve Lapouble,Gaëlle Pierron,Sandrine Grossetête-Lalami,Sylvain Baulande,Gudrun Schleiermacher,Emmanuel Barillot,Hermann Rohrer,Olivier Delattre,Olivier Delattre,Isabelle Janoueix-Lerosey,Isabelle Janoueix-Lerosey +35 more
TL;DR: This work discovered three types of identity in neuroblastoma cell lines: a sympathetic noradrenergic identity, defined by a CRC module including the PHOX2B, HAND2 and GATA3 transcription factors (TFs); an NCC-like identity, driven by aRC module containing AP-1 TFs; and a mixed type, further deconvoluted at the single-cell level.
Journal ArticleDOI
Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients.
Jordan Madic,Jordan Madic,Anna Kiialainen,François-Clément Bidard,Fabian Birzele,Guillemette Ramey,Quentin Leroy,Thomas Rio Frio,Isabelle Vaucher,Virginie Raynal,Virginie Bernard,Alban Lermine,Inga Clausen,Nicolas Giroud,Roland Schmucki,Maud Milder,Maud Milder,Carsten Horn,Olivia Spleiss,Olivier Lantz,Olivier Lantz,Marc-Henri Stern,Marc-Henri Stern,Jean-Yves Pierga,Jean-Yves Pierga,Martin Weisser,Ronald Lebofsky +26 more
TL;DR: In this article, the authors used the high prevalence of TP53 mutations in triple negative breast cancer (TNBC) to compare ctDNA and CTC detection rates and prognostic value in metastatic TNBC patients.
Journal ArticleDOI
Bioinformatics for precision medicine in oncology: principles and application to the SHIVA clinical trial.
Nicolas Servant,Nicolas Servant,Nicolas Servant,Julien Roméjon,Julien Roméjon,Julien Roméjon,Pierre Gestraud,Pierre Gestraud,Pierre Gestraud,Philippe La Rosa,Philippe La Rosa,Philippe La Rosa,Georges Lucotte,Georges Lucotte,Georges Lucotte,Séverine Lair,Séverine Lair,Séverine Lair,Virginie Bernard,Bruno Zeitouni,Bruno Zeitouni,Bruno Zeitouni,Fanny Coffin,Fanny Coffin,Fanny Coffin,Gerome Jules-Clement,Florent Yvon,Florent Yvon,Florent Yvon,Alban Lermine,Alban Lermine,Alban Lermine,Patrick Poullet,Patrick Poullet,Patrick Poullet,Stéphane Liva,Stéphane Liva,Stéphane Liva,Stuart Pook,Stuart Pook,Stuart Pook,Tatiana Popova,Tatiana Popova,Camille Barette,François Prud'homme,Jean Gabriel Dick,Maud Kamal,Christophe Le Tourneau,Christophe Le Tourneau,Christophe Le Tourneau,Emmanuel Barillot,Emmanuel Barillot,Emmanuel Barillot,Philippe Hupé +53 more
TL;DR: The complete bioinformatics environment and the key points of its implementation are presented in the context of the SHIVA clinical trial, a multicentric randomized phase II trial comparing targeted therapy based on tumor molecular profiling versus conventional therapy in patients with refractory cancer.
Journal ArticleDOI
Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.
Valentina Boeva,Valentina Boeva,Valentina Boeva,Stéphanie Jouannet,Romain Daveau,Valérie Combaret,Cécile Pierre-Eugène,Alex Cazes,Caroline Louis-Brennetot,Gudrun Schleiermacher,Sandrine Ferrand,Gaëlle Pierron,Alban Lermine,Alban Lermine,Alban Lermine,Thomas Rio Frio,Virginie Raynal,Gilles Vassal,Emmanuel Barillot,Emmanuel Barillot,Emmanuel Barillot,Olivier Delattre,Isabelle Janoueix-Lerosey +22 more
TL;DR: It is indicated that both non-homologous end joining-mediated repair and replicative processes may account for genomic rearrangements in neuroblastoma.
Journal ArticleDOI
Nebula--a web-server for advanced ChIP-seq data analysis.
TL;DR: Nebula is an innovative web service that provides an advanced ChIP-seq analysis pipeline providing ready-to-publish results and is designed for both bioinformaticians and biologists.