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Albert I. Meyers

Bio: Albert I. Meyers is an academic researcher from Colorado State University. The author has contributed to research in topics: Enantioselective synthesis & Bicyclic molecule. The author has an hindex of 63, co-authored 627 publications receiving 16261 citations. Previous affiliations of Albert I. Meyers include Texas A&M University & Louisiana State University.


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TL;DR: The use of chiral oxazolines as ligands in asymmetric catalysis has been extensively studied in the literature as mentioned in this paper, with a large number of important publications detailing oxazoline-related chemistry, suggesting that research in this area, as in synthetic organic chemistry in general, has yet to mature.

492 citations

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TL;DR: In this article, the formation of chiral amino alcohols by reduction of amino acids has been the subject of considerable effort due to their importance in asymmetric synthesis? peptide and pharmaceutical chemistry: resolution of racemic mixtures: synthesis of insecticidal compounds: and others.
Abstract: The formation of chiral amino alcohols by reduction of amino acids has been the subject of considerable effort due to their importance in asymmetric synthesis? peptide and pharmaceutical chemistry: resolution of racemic mixtures: synthesis of insecticidal compounds: and others. From the earliest reports by Karrer in 1921, amino alcohols were prepared by reduction of the corresponding amino acid esters with sodium in ethanol.& Subsequently, lithium aluminum hydride6b and sodium borohydride& were employed and furthermore, free amino acids were shown to be reduced directly by sodium bis(2-methoxyethoxy)aluminum hydride? the borane-dimethyl sulfide complex activated by boron trifluoride-etherate,w lithium aluminum hydride? lithium borohyride with trimethylchl~rosilane,~~ sodium borohydride-trimethyl~hlorosilane,~g or boron trif l~orideetherate.~~ Very recently, while this manuscript was being prepared, a report appeared describing an efficient reduction of amino acids and derivatives using sodium borohydride and sulfuric

484 citations


Cited by
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TL;DR: An overview of the basic photophysics and electron transfer theory is presented in order to provide a comprehensive guide for employing this class of catalysts in photoredox manifolds.
Abstract: In this review, we highlight the use of organic photoredox catalysts in a myriad of synthetic transformations with a range of applications. This overview is arranged by catalyst class where the photophysics and electrochemical characteristics of each is discussed to underscore the differences and advantages to each type of single electron redox agent. We highlight both net reductive and oxidative as well as redox neutral transformations that can be accomplished using purely organic photoredox-active catalysts. An overview of the basic photophysics and electron transfer theory is presented in order to provide a comprehensive guide for employing this class of catalysts in photoredox manifolds.

3,550 citations

Journal ArticleDOI
TL;DR: P palladium and ruthenium catalysts have been described that enable the direct arylation of (hetero)arenes with challenging coupling partners--including electrophilic aryl chlorides and tosylates as well as simple arenes in cross-dehydrogenative arylations.
Abstract: The area of transition-metal-catalyzed direct arylation through cleavage of CH bonds has undergone rapid development in recent years, and is becoming an increasingly viable alternative to traditional cross-coupling reactions with organometallic reagents In particular, palladium and ruthenium catalysts have been described that enable the direct arylation of (hetero)arenes with challenging coupling partners—including electrophilic aryl chlorides and tosylates as well as simple arenes in cross-dehydrogenative arylations Furthermore, less expensive copper, iron, and nickel complexes were recently shown to be effective for economically attractive direct arylations

2,408 citations

Journal ArticleDOI
TL;DR: I. Foldamer Research 3910 A. Backbones Utilizing Bipyridine Segments 3944 1.
Abstract: III. Foldamer Research 3910 A. Overview 3910 B. Motivation 3910 C. Methods 3910 D. General Scope 3912 IV. Peptidomimetic Foldamers 3912 A. The R-Peptide Family 3913 1. Peptoids 3913 2. N,N-Linked Oligoureas 3914 3. Oligopyrrolinones 3915 4. Oxazolidin-2-ones 3916 5. Azatides and Azapeptides 3916 B. The â-Peptide Family 3917 1. â-Peptide Foldamers 3917 2. R-Aminoxy Acids 3937 3. Sulfur-Containing â-Peptide Analogues 3937 4. Hydrazino Peptides 3938 C. The γ-Peptide Family 3938 1. γ-Peptide Foldamers 3938 2. Other Members of the γ-Peptide Family 3941 D. The δ-Peptide Family 3941 1. Alkene-Based δ-Amino Acids 3941 2. Carbopeptoids 3941 V. Single-Stranded Abiotic Foldamers 3944 A. Overview 3944 B. Backbones Utilizing Bipyridine Segments 3944 1. Pyridine−Pyrimidines 3944 2. Pyridine−Pyrimidines with Hydrazal Linkers 3945

1,922 citations

Journal ArticleDOI
TL;DR: Using R-Hydroxy Stannanes as a Model for a Methylenation Reaction and Conclusions and Future Prospects are presented.
Abstract: 6.4. Polyynes 3123 6.5. Using R-Hydroxy Stannanes 3124 6.6. Using the Hurtley Reaction 3124 6.7. Using a Methylenation Reaction 3125 7. Conclusions and Future Prospects 3125 8. Uncommon Abbreviations 3125 9. Acknowledgments 3125 10. Note Added in Proof 3125 11. References 3126 * Authorstowhomcorrespondenceshouldbeaddressed(evano@chimie.uvsq.fr, nicolas.blanchard@uha.fr). † Université de Versailles Saint Quentin en Yvelines. ‡ Université de Haute-Alsace. Chem. Rev. 2008, 108, 3054–3131 3054

1,789 citations