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Alberto Mantovani

Researcher at Humanitas University

Publications -  1464
Citations -  187196

Alberto Mantovani is an academic researcher from Humanitas University. The author has contributed to research in topics: Inflammation & Chemokine. The author has an hindex of 183, co-authored 1397 publications receiving 163826 citations. Previous affiliations of Alberto Mantovani include University of Milan & Mario Negri Institute for Pharmacological Research.

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Cancer-related inflammation.

TL;DR: The molecular pathways of this cancer-related inflammation are now being unravelled, resulting in the identification of new target molecules that could lead to improved diagnosis and treatment.
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Inflammation and cancer: back to Virchow?

TL;DR: A rationale for the use of cytokine and chemokine blockade, and further investigation of non-steroidal anti-inflammatory drugs, in the chemoprevention and treatment of malignant diseases is provided.
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The chemokine system in diverse forms of macrophage activation and polarization.

TL;DR: Recent evidence suggests that differential modulation of the chemokine system integrates polarized macrophages in pathways of resistance to, or promotion of, microbial pathogens and tumors, or immunoregulation, tissue repair and remodeling.
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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

TL;DR: These functionally polarized cells, and similarly oriented or immature dendritic cells present in tumors, have a key role in subversion of adaptive immunity and in inflammatory circuits that promote tumor growth and progression.
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Macrophage plasticity and polarization: in vivo veritas

TL;DR: The identification of mechanisms and molecules associated with macrophage plasticity and polarized activation provides a basis for Macrophage-centered diagnostic and therapeutic strategies.