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Alec B. O'Connor
Researcher at University of Rochester
Publications - 69
Citations - 6616
Alec B. O'Connor is an academic researcher from University of Rochester. The author has contributed to research in topics: Clinical trial & Neuropathic pain. The author has an hindex of 23, co-authored 63 publications receiving 5966 citations. Previous affiliations of Alec B. O'Connor include Indiana University & University of Rochester Medical Center.
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Journal ArticleDOI
Pharmacologic management of neuropathic pain: evidence-based recommendations.
Robert H. Dworkin,Alec B. O'Connor,Miroslav Backonja,John T. Farrar,Nanna B. Finnerup,Troels S. Jensen,Eija Kalso,John D. Loeser,Christine Miaskowski,Turo Nurmikko,Russell K. Portenoy,Andrew S.C. Rice,Brett R. Stacey,Rolf-Detlef Treede,Dennis C. Turk,Mark S. Wallace +15 more
TL;DR: Patients with neuropathic pain are challenging to manage and evidence‐based clinical recommendations for pharmacologic management are needed, and medications should be individualized, considering side effects, potential beneficial or deleterious effects on comorbidities, and whether prompt onset of pain relief is necessary.
Journal ArticleDOI
Neuropathic pain: quality-of-life impact, costs and cost effectiveness of therapy.
TL;DR: Head-to-head clinical trials comparing NP therapies are needed to help assess the relative clinical efficacy of treatments, ideally using HR-QOL and utility outcomes, and to facilitate future cost-effectiveness research in NP.
Journal ArticleDOI
Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update
Robert H. Dworkin,Alec B. O'Connor,Joseph Audette,Ralf Baron,Geoffrey K. Gourlay,Maija Haanpää,Joel L. Kent,Elliot J. Krane,Elliot J. Krane,Alyssa Lebel,Robert M. Levy,Sean Mackey,John M. Mayer,Christine Miaskowski,Srinivasa N. Raja,Andrew S.C. Rice,Kenneth E. Schmader,Brett R. Stacey,Steven P. Stanos,Rolf-Detlef Treede,Dennis C. Turk,Gary A. Walco,Christopher D. Wells +22 more
TL;DR: A review of the evidence-based guidelines for the pharmacological treatment of neuropathic pain can be found in this article, where botulinum toxin, high-concentration capsaicin patch, lacosamide, selective serotonin reuptake inhibitors, and combination therapies are presented.
Journal ArticleDOI
Treatment of Neuropathic Pain: An Overview of Recent Guidelines
TL;DR: The International Association for the Study of Pain (IASP) Neuropathic Pain Special Interest Group (NeuPSIG) developed evidence-based guidelines for the pharmacologic management of neuropathic pain that take into account clinical efficacy, adverse effects, impact on health-related quality of life, convenience, and costs as mentioned in this paper.
Journal ArticleDOI
Pain associated with multiple sclerosis: Systematic review and proposed classification
TL;DR: A systematic review of the literature describing pain in MS patients spans four decades and has employed a range of different methodologies to summarize current understanding of the association between MS and pain to provide a basis for the design and interpretation of future studies.