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Alejandro F. Castro
Researcher at Johns Hopkins University
Publications - 4
Citations - 18842
Alejandro F. Castro is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Kidney disease & Renal function. The author has an hindex of 4, co-authored 4 publications receiving 14898 citations.
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Journal ArticleDOI
A New Equation to Estimate Glomerular Filtration Rate
Andrew S. Levey,Lesley A. Stevens,Christopher H. Schmid,Yaping (Lucy) Zhang,Alejandro F. Castro,Harold I. Feldman,John W. Kusek,Paul W. Eggers,Frederick Van Lente,Tom Greene,Josef Coresh +10 more
TL;DR: The CKD-EPI creatinine equation is more accurate than the Modification of Diet in Renal Disease Study equation and could replace it for routine clinical use.
Journal ArticleDOI
CKD surveillance using laboratory data from the population-based National Health and Nutrition Examination Survey (NHANES).
Alejandro F. Castro,Josef Coresh +1 more
TL;DR: Surveillance for chronic kidney disease using nationally representative samples of the US population is central in providing information about the magnitude and trends in CKD burden that will guide disease management and prevention planning for clinicians and public health authorities.
Journal ArticleDOI
Anesthetic Choice of Halothane Versus Propofol: Impact on Experimental Perioperative Stroke
TL;DR: It is demonstrated that short-duration halothane exposure before MCAO in the awakening animal attenuates infarction volume compared with propofol, which may activate secondary injury pathways, which negate the protective effects of short-term halothan preischemic treatment.
Journal ArticleDOI
Treatment With the Competitive NMDA Antagonist GPI 3000 Does Not Improve Outcome After Cardiac Arrest in Dogs
Mark A. Helfaer,Rebecca N. Ichord,Lee J. Martin,Patricia D. Hurn,Alejandro F. Castro,Richard J. Traystman +5 more
TL;DR: Contrary to results seen in experimental global and focal cerebral ischemia, receptor antagonism with GPI does not improve brain outcome after cardiac arrest and resuscitation in the dog, and behavioral and histological outcomes both were worsened by GPI treatment at two doses, and mortality was higher relative to saline control treatment.