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Alejandro Reyes
Researcher at University of Los Andes
Publications - 64
Citations - 6017
Alejandro Reyes is an academic researcher from University of Los Andes. The author has contributed to research in topics: Gene & Biology. The author has an hindex of 21, co-authored 57 publications receiving 4681 citations. Previous affiliations of Alejandro Reyes include University of Washington & Max Planck Society.
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Journal ArticleDOI
The shared antibiotic resistome of soil bacteria and human pathogens
Kevin J. Forsberg,Alejandro Reyes,Bin Wang,Elizabeth M. Selleck,Morten Otto Alexander Sommer,Morten Otto Alexander Sommer,Gautam Dantas +6 more
TL;DR: Multidrug-resistant soil bacteria containing resistance cassettes against five classes of antibiotics are described that have perfect nucleotide identity to genes from diverse human pathogens, offering not only evidence of lateral exchange but also a mechanism by which antibiotic resistance disseminates.
Journal ArticleDOI
Viruses in the faecal microbiota of monozygotic twins and their mothers
Alejandro Reyes,Matthew Haynes,Nicole Hanson,Florent E. Angly,Florent E. Angly,Andrew C. Heath,Forest Rohwer,Jeffrey I. Gordon +7 more
TL;DR: In this article, the viromes (metagenomes) of virus-like particles isolated from faecal samples collected from healthy adult female monozygotic twins and their mothers at three time points over a one-year period.
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Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice
Andrew L. Goodman,George Kallstrom,Jeremiah J. Faith,Alejandro Reyes,Aimee Moore,Gautam Dantas,Jeffrey I. Gordon +6 more
TL;DR: High-throughput anaerobic culturing techniques with gnotobiotic animal husbandry and metagenomics are combined to show that the human fecal microbiota consists largely of taxa and predicted functions that are represented in its readily cultured members.
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Going viral: next-generation sequencing applied to phage populations in the human gut.
TL;DR: How work characterizing phage diversity and lifestyles in the human gut is changing the authors' view of ourselves as supra-organisms is explored and how a renewed appreciation of phage dynamics may yield new applications for phage therapies designed to manipulate the structure and functions of their gut microbiomes is discussed.
Journal ArticleDOI
Minimum information about an uncultivated virus genome (MIUVIG)
Simon Roux,Evelien M. Adriaenssens,Bas E. Dutilh,Eugene V. Koonin,Andrew M. Kropinski,Mart Krupovic,Jens H. Kuhn,Rob Lavigne,J. Rodney Brister,Arvind Varsani,Arvind Varsani,Clara Amid,Ramy K. Aziz,Seth R. Bordenstein,Peer Bork,Mya Breitbart,Guy Cochrane,Rebecca A. Daly,Christelle Desnues,Melissa B. Duhaime,Joanne B. Emerson,François Enault,Jed A. Fuhrman,Pascal Hingamp,Philip Hugenholtz,Bonnie L. Hurwitz,Natalia Ivanova,Jessica M. Labonté,Kyung Bum Lee,Rex R. Malmstrom,Manuel Martinez-Garcia,Ilene Karsch Mizrachi,Hiroyuki Ogata,David Paez-Espino,Marie-Agnès Petit,Catherine Putonti,Thomas Rattei,Alejandro Reyes,Francisco Rodriguez-Valera,Karyna Rosario,Lynn M. Schriml,Frederik Schulz,Grieg F. Steward,Matthew B. Sullivan,Shinichi Sunagawa,Curtis A. Suttle,Ben Temperton,Susannah G. Tringe,Rebecca Vega Thurber,Nicole S. Webster,Nicole S. Webster,Katrine Whiteson,Steven W. Wilhelm,K. Eric Wommack,Tanja Woyke,Kelly C. Wrighton,Pelin Yilmaz,Takashi Yoshida,Mark J. Young,Natalya Yutin,Lisa Zeigler Allen,Lisa Zeigler Allen,Nikos C. Kyrpides,Emiley A. Eloe-Fadrosh +63 more
TL;DR: The MIUViG (Minimum Information about an Uncultivated Virus Genome) as mentioned in this paper standard was developed within the Genomic Standards Consortium framework and includes virus origin, genome quality, genome annotation, taxonomic classification, biogeographic distribution and in silico host prediction.