Aleksandra Zatajska

Bio: Aleksandra Zatajska is an academic researcher from University of Wrocław. The author has contributed to research in topics: Condensation reaction & Triazole. The author has an hindex of 3, co-authored 4 publications receiving 22 citations.

A Study on the Condensation Reaction of 4-Amino-3,5-dimethyl-1,2,4-triazole with Benzaldehydes: Structure and Spectroscopic Properties of Some New Stable Hemiaminals

Abstract: Studies on the stable hemiaminals and Schiff bases formation in the reaction of substituted benzaldehydes with primary 3,5-dimethyl-1,2,4-triazole 4-amine were carried out under neutral conditions. These products were investigated by IR, Raman, MS, ¹H- and (13)C-NMR spectra as well as by X-ray crystallography. The effect of reaction conditions: temperature, polarity of the solvents utilized, substrate concentration and the ortho and para benzaldehyde substituents on the yield of products was also examined.

4-amino-3,5-dimethyl-4h-1,2,4-triazole derivatives, method of preparation thereof, a pharmaceutical compound containing the same and use thereof

Abstract: The object of the invention are new 4-amino-3,5-dimethyl-4H-l,2,4-triazole derivatives, a method of preparation thereof, a pharmaceutical compound containing the new compounds and use thereof. These are new compounds obtained in a reaction of 4-amino-3,5-dimethyl-4H-l,2,4- triazole with benzaldehyde derivatives. The compounds are characterized by chirality centers and ensuing advantageous chemical and biological properties. The new triazole derivatives may be used as active principles of medicaments for preventing and/or treating infections caused by the presence of fungi or bacteria.

Synthesis, Characterization and Biological Activity of New 3-substitued-4-amino-5-hydrazino-1,2,4-triazole Schiff Bases and Their Cu(II) Complexes: A New Approach to CuO Nanoparticles for Photocatalytic Degradation of Methylene Blue Dye

Abstract: Three new Schiff base compounds were synthesized via condensation of 3-R-4-amino-5-hydrazino-1,2,4-triazole with dibenzoylmethane [R = H, CH3, and CH2CH3 namely L1, L2, and L3, respectively]. The synthesized Schiff bases were characterized using melting point, CHN elemental analyses, FT-IR, and 1H-NMR. The corresponding Cu(II) Schiff base complexes were synthesized via refluxing the prepared Schiff bases with CuCl2·2H2O. The synthesized complexes have been characterized by means of different spectral tools (FT-IR, ESR, and UV–Vis spectra) in addition to elemental analysis, magnetic moment, conductivity, and thermal analysis. The synthesized copper complexes are nonelectrolytes in N,N-dimethylformamide (DMF) based on their conductance values. Using modified Bauer-Kirby method, the Schiff bases and their Cu(II) complexes have been tested for antifungal (Candida albicans and Aspergillus flavus) and antibacterial (Staphylococcus aureus and Escherichia coli) activities. Moreover, CuO nanoparticles were produced via thermal decomposition of the synthesized Cu(II) complexes at 650 °C. The produced nanoparticles were characterized using XRD, HR-TEM, FT-IR, and UV–Vis spectroscopy. The CuO nanostructures exhibited good photocatalytic activity for the degradation of methylene blue dye in the presence of hydrogen peroxide with 77.36% degradation efficiency in 360 min. Proposed structure of the synthesized Cu(II) complexes