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Aleksei A. Chmura
Researcher at EcoHealth Alliance
Publications - 29
Citations - 3181
Aleksei A. Chmura is an academic researcher from EcoHealth Alliance. The author has contributed to research in topics: Animal ecology & Coronavirus. The author has an hindex of 15, co-authored 27 publications receiving 2444 citations. Previous affiliations of Aleksei A. Chmura include University of São Paulo.
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Journal ArticleDOI
Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
Xing-Yi Ge,Jia Lu Li,Xing-Lou Yang,Aleksei A. Chmura,Guangjian Zhu,Jonathan H. Epstein,Jonna A. K. Mazet,Ben Hu,Wei Zhang,Cheng Peng,Yu Ji Zhang,Chu Ming Luo,Bing Tan,Ning Wang,Yan Zhu,Gary Crameri,Shuyi Zhang,Lin-Fa Wang,Lin-Fa Wang,Peter Daszak,Zhengli Shi +20 more
TL;DR: These results provide the strongest evidence to date that Chinese horseshoe bats are natural reservoirs of SARS-CoV, and that intermediate hosts may not be necessary for direct human infection by some bat SL-CoVs, and highlight the importance of pathogen-discovery programs targeting high-risk wildlife groups in emerging disease hotspots.
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Predicting the global spread of H5N1 avian influenza.
A. Marm Kilpatrick,Aleksei A. Chmura,David W. Gibbons,Robert C. Fleischer,Peter P. Marra,Peter Daszak +5 more
TL;DR: H5N1 is more likely to be introduced into the Western Hemisphere through infected poultry and into the mainland United States by subsequent movement of migrating birds from neighboring countries, rather than from eastern Siberia.
Journal ArticleDOI
Origin and cross-species transmission of bat coronaviruses in China.
Alice Latinne,Alice Latinne,Ben Hu,Kevin J. Olival,Guangjian Zhu,Libiao Zhang,Hongying Li,Aleksei A. Chmura,Hume Field,Hume Field,Carlos Zambrana-Torrelio,Jonathan H. Epstein,Bei Li,Wei Zhang,Lin-Fa Wang,Zhengli Shi,Peter Daszak +16 more
TL;DR: It is found that alpha-CoVs have switched hosts more frequently than betaCoVs, and a bat family and genus that are highly involved in host-switching are identified, which define hotspots of CoV evolutionary diversity.
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Serological Evidence of Bat SARS-Related Coronavirus Infection in Humans, China
Ning Wang,Shi-Yue Li,Xing-Lou Yang,Hui-Min Huang,Yuji Zhang,Hua Guo,Chu-Ming Luo,Maureen Miller,Guangjian Zhu,Aleksei A. Chmura,Emily Hagan,Ji-Hua Zhou,Yun-Zhi Zhang,Lin-Fa Wang,Peter Daszak,Zhengli Shi +15 more
TL;DR: This report developed a specific ELISA based on the nucleocapsid protein of a SARSr-CoV strain and detected its antibody in humans who are highly exposed to bat populations and demonstrated the Sarsr- CoV had spillover to humans, although did not cause clinical diseases.
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Comparative analysis of rodent and small mammal viromes to better understand the wildlife origin of emerging infectious diseases
Zhiqiang Wu,Liang Lu,Jiang Du,Li Yang,Xianwen Ren,Bo Liu,Jinyong Jiang,Jian Yang,Jie Dong,Lilian Sun,Yafang Zhu,Yuhui Li,Dandan Zheng,Chi Zhang,Haoxiang Su,Yu-ting Zheng,Hongning Zhou,Guangjian Zhu,Hongying Li,Aleksei A. Chmura,Fan Yang,Peter Daszak,Jianwei Wang,Qiyong Liu,Qi Jin +24 more
TL;DR: The results expand the understanding of the viromes of rodents and insectivores in China and suggest that there is high diversity of viruses awaiting discovery in these species in Asia.