Alessandra Tammaro

TL;DR: This research presents a novel probabilistic procedure that allows us to assess the importance of knowing the carrier and removal status of canine coronavirus in the context of infectious disease.

TL;DR: An extensive overview of TREM‐1 in non‐infectious diseases, with the focus on the therapeutic potential of Trem‐1 intervention strategies herein, and a functional enrichment analysis of T REM‐1 signaling pathway and potential TREM-1 ligands in these diseases, obtained via in silico approach.

TL;DR: S100A8/A9 plays a crucial part in controlling macrophage-mediated renal repair following I/R, as reflected by increased renal damage, sustained inflammation, induction of fibrosis, and increased expression of collagens.

TL;DR: An overview of the past 5 years of research on the role of innate immunity in experimental and human IRI is provided, with a focus on the cascade of events activated by hypoxic damage in TECs: from programmed cell death (PCD) and mitochondrial dysfunction-mediated metabolic rewiring of T ECs to maladaptive repair and progression to fibrosis.

TL;DR: It is demonstrated that S100A8/A9 mediates renal damage and fibrosis, presumably through loss of tubular epithelial cell contacts and irreversible damage, and could be a therapeutic strategy to halt renal fibrosis in patients with chronic kidney disease.