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Alessio Fasano
Researcher at Harvard University
Publications - 519
Citations - 42435
Alessio Fasano is an academic researcher from Harvard University. The author has contributed to research in topics: Zonulin & Medicine. The author has an hindex of 96, co-authored 478 publications receiving 34580 citations. Previous affiliations of Alessio Fasano include Columbia University & Henry M. Jackson Foundation for the Advancement of Military Medicine.
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Journal ArticleDOI
Chronic inflammation in the etiology of disease across the life span
David Furman,Judith Campisi,Judith Campisi,Eric Verdin,Pedro Carrera-Bastos,Sasha Targ,Claudio Franceschi,Luigi Ferrucci,Derek W. Gilroy,Alessio Fasano,Gary W. Miller,Andrew H. Miller,Alberto Mantovani,Alberto Mantovani,Alberto Mantovani,Cornelia M. Weyand,Nir Barzilai,Jorge Goronzy,Thomas A. Rando,Thomas A. Rando,Rita B. Effros,Alejandro Lucia,Nicole Kleinstreuer,George M. Slavich +23 more
TL;DR: The multi-level mechanisms underlying SCI and several risk factors that promote this health-damaging phenotype, including infections, physical inactivity, poor diet, environmental and industrial toxicants and psychological stress are described.
Journal ArticleDOI
Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: A large multicenter study
Alessio Fasano,Irene Berti,Tania Gerarduzzi,Tarcisio Not,Richard B. Colletti,Sandro Drago,Yoram Elitsur,Peter H.R. Green,Stefano Guandalini,Ivor D. Hill,Michelle Pietzak,Alessandro Ventura,Mary Thorpe,Debbie Kryszak,Fabiola Fornaroli,Steven S. Wasserman,Joseph A. Murray,Karoly Horvath +17 more
TL;DR: The results suggest that CD occurs frequently not only in patients with gastrointestinal symptoms, but also in first- and second-degree relatives and patients with numerous common disorders even in the absence of gastrointestinal symptoms.
Journal ArticleDOI
The Oslo definitions for coeliac disease and related terms
Jonas F. Ludvigsson,Daniel A. Leffler,Julio C. Bai,Federico Biagi,Alessio Fasano,Peter H.R. Green,Marios Hadjivassiliou,Katri Kaukinen,Ciaran P. Kelly,Jonathan N. Leonard,Knut E.A. Lundin,Joseph A. Murray,David S Sanders,David S Sanders,Marjorie M. Walker,Fabiana Zingone,Carolina Ciacci +16 more
TL;DR: A multidisciplinary task force of 16 physicians from seven countries used the electronic database PubMed to review the literature for CD-related terms and suggested a definition for each term, followed by feedback through a web survey on definitions and discussions during a meeting in Oslo.
Journal ArticleDOI
Current approaches to diagnosis and treatment of celiac disease: An evolving spectrum☆
Alessio Fasano,Carlo Catassi +1 more
TL;DR: The current gold standard for the diagnosis of CD remains histologic confirmation of the intestinal damage in serologically positive individuals, and the keystone treatment of CD patients is a lifelong elimination diet in which food products containing gluten are avoided.
Journal ArticleDOI
Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.
Ivor D. Hill,Martha H. Dirks,Gregory S. Liptak,Richard B. Colletti,Alessio Fasano,Stefano Guandalini,Edward J. Hoffenberg,Karoly Horvath,Joseph A. Murray,Mitchell Pivor,Ernest G. Seidman +10 more
TL;DR: It is recommended that children and adolescents with symptoms of celiac disease or an increased risk for Celiac disease have a blood test for antibody to tissue transglutaminase (TTG), and that those with an elevated TTG be referred to a pediatric gastroenterologist for an intestinal biopsy and treated with a strict gluten-free diet.