Alex Ieng Kin Lao

TL;DR: In this article, anodic bonding between Si-based and glass substrates has been characterized in detail, and the effects of magnitude of applied voltage, surface properties (coating of Si substrate), and surface cleanliness (pre-bonding cleaning procedure) on the time required for complete bonding were thoroughly studied.

TL;DR: A novel method for the fast identification of genetic material utilizing a micro-DNA amplification and analysis device (micro-DAAD) consisting of multiple PCR microreactors with integrated DNA microarrays was developed and successful amplification of the genetic material and the consecutive analysis of the fluorescent-labeled amplicons by the integrated oligonucleotide probes were demonstrated.

TL;DR: In this paper, a silicon-based micromachined fluidic chamber with integrated platinum heaters and sensors has been developed and thermally well characterized, which is highly applicable to both gas and liquid phase reactions that require excellent thermal control.

TL;DR: Two stringency control strategies are used for single base mismatch discrimination, namely adding a denaturant, i.e. formamide (FA), into hybridization buffer and coupling negative potentials for selective dehybridization of mismatch DNA.

TL;DR: Pulsed voltage offers more parameters compared to the constant voltage mode, e.g., pulse frequency, duty cycle, and waveform to optimize the retention behavior of analytes and improved separation of polystyrene particles of different surface charge and particle size is demonstrated.