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Alex J. Kind
Researcher at Technische Universität München
Publications - 8
Citations - 5420
Alex J. Kind is an academic researcher from Technische Universität München. The author has contributed to research in topics: Somatic cell nuclear transfer & Cellular differentiation. The author has an hindex of 7, co-authored 8 publications receiving 5237 citations. Previous affiliations of Alex J. Kind include The Roslin Institute.
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Viable offspring derived from fetal and adult mammalian cells
TL;DR: The birth of lambs from differentiated fetal and adult cells confirms that differentiation of that cell did not involve the irreversible modification of genetic material required for development to term and reinforces previous speculation that by inducing donor cells to become quiescent it will be possible to obtain normal development from a wide variety of differentiated cells.
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Viable offspring derived from fetal and adult mammalian cells.
TL;DR: Dolly was the first sheep cloned and developed from the nuclei of fully differentiated adult cells, rather than from theuclei of early embryonic cells.
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Conservation of IGF2-H19 and IGF2R imprinting in sheep: effects of somatic cell nuclear transfer
Lorraine E. Young,Angelika Schnieke,Kenneth J. McCreath,Sébastien Wieckowski,Galia Konfortova,Kenneth Fernandes,Grazyna Ptak,Alex J. Kind,Ian Wilmut,Pasqualino Loi,Robert Feil,Robert Feil +11 more
TL;DR: Data indicate that somatic cell nuclear transfer procedures can lead to epigenetic deregulation at imprinted loci in sheep, and the underlying mechanisms remain to be determined.
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DNA microsatellite analysis of Dolly
David Ashworth,Matthew Bishop,Keith H.S. Campbell,Alan Colman,Alex J. Kind,Angelika Schnieke,Sarah C. Blott,H Griffin,Chris Haley,Jim McWhir,Ian Wilmut +10 more
TL;DR: A more detailed microsatellite analysis, which confirms the origin of Dolly, the first animal cloned from an adult mammal, was produced by somatic cell nuclear transfer from a cell population derived from mammary tissue taken from a 6-year-old Finn Dorset ewe.