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Alexander A. Hanke
Researcher at Hannover Medical School
Publications - 63
Citations - 3303
Alexander A. Hanke is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Thromboelastometry & Prothrombin complex concentrate. The author has an hindex of 25, co-authored 62 publications receiving 2993 citations. Previous affiliations of Alexander A. Hanke include Hochschule Hannover.
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Journal ArticleDOI
First-line Therapy with Coagulation Factor Concentrates Combined with Point-of-Care Coagulation Testing Is Associated with Decreased Allogeneic Blood Transfusion in Cardiovascular Surgery A Retrospective, Single-center Cohort Study
Klaus Görlinger,Daniel Dirkmann,Alexander A. Hanke,Markus Kamler,Eva Kottenberg,Matthias Thielmann,Heinz Jakob,Jürgen Peters +7 more
TL;DR: First-line administration of coagulation factor concentrates combined with point-of-care testing was associated with decreased incidence of blood transfusion and thrombotic/thromboembolic events.
Journal ArticleDOI
Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy
Herbert Schöchl,Ulrike Nienaber,Marc Maegele,Gerald Hochleitner,Florian Primavesi,Beatrice Steitz,Christian Arndt,Alexander A. Hanke,Wolfgang G. Voelckel,Cristina Solomon +9 more
TL;DR: TEM-guided haemostatic therapy with fibrinogen concentrate and PCC reduced the exposure of trauma patients to allogeneic blood products.
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Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial.
Niels Rahe-Meyer,Cristina Solomon,Alexander A. Hanke,Dirk S. Schmidt,Dietrich Knoerzer,Gerald Hochleitner,Benny Sørensen,Christian Hagl,Maximilian Pichlmaier +8 more
TL;DR: Hemostatic therapy with fibrinogen concentrate in patients undergoing aortic surgery significantly reduced the transfusion of allogeneic blood products.
Journal ArticleDOI
Platelet function following trauma. A multiple electrode aggregometry study.
Cristina Solomon,Stefan Traintinger,Bernhard Ziegler,Alexander A. Hanke,Niels Rahe-Meyer,Wolfgang G. Voelckel,Herbert Schöchl +6 more
TL;DR: A retrospective analysis of patients admitted to the emergency room at the AUVA Trauma Centre, Salzburg, after sustaining traumatic injury found minor decreases in platelet function upon admission to the ER were a sign of coagulopathy accompanying increased mortality in patients with trauma.
Journal ArticleDOI
Reduction of Fresh Frozen Plasma Requirements by Perioperative Point-of-Care Coagulation Management with Early Calculated Goal-Directed Therapy.
Klaus Görlinger,Dietmar Fries,Daniel Dirkmann,Christian F Weber,Alexander A. Hanke,Herbert Schöchl +5 more
TL;DR: The implementation of perioperative POC coagulation management algorithms based on early, calculated, goaldirected therapy with fibrinogen concentrate and PCC is associated with a reduction in the transfusion requirements for FFP, PRBC and platelets as well as with a reduced incidence of massive transfusion.