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Alexander Burges
Researcher at Ludwig Maximilian University of Munich
Publications - 193
Citations - 6461
Alexander Burges is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 36, co-authored 154 publications receiving 4912 citations. Previous affiliations of Alexander Burges include Charité & Curie Institute.
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Journal ArticleDOI
Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer.
Isabelle Ray-Coquard,Patricia Pautier,Sandro Pignata,David Pérol,Antonio González-Martín,Regina Berger,Keiichi Fujiwara,Ignace Vergote,Nicoletta Colombo,J. Maenpaa,Frédéric Selle,Jalid Sehouli,Domenica Lorusso,Eva Guerra Alia,Alexander Reinthaller,Shoji Nagao,C. Lefeuvre-Plesse,Ulrich Canzler,Giovanni Scambia,Alain Lortholary,Frederik Marmé,Pierre Combe,Nikolaus de Gregorio,Manuel Rodrigues,Paul Buderath,Coraline Dubot,Alexander Burges,Benoit You,Eric Pujade-Lauraine,Philipp Harter +29 more
TL;DR: In patients with advanced ovarian cancer receiving first-line standard therapy including bevacizumab, the addition of maintenance olaparib provided a significant progression-free survival benefit, which was substantial in patients with HRD-positive tumors, including those without a BRCA mutation.
Journal ArticleDOI
The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial
Markus M. Heiss,Pawel Murawa,Piotr Koralewski,Elzbieta Kutarska,Olena O. Kolesnik,Vladimir V. Ivanchenko,Alexander S. Dudnichenko,Birute Aleknaviciene,Arturas Razbadauskas,Martin Gore,Elena Ganea-Motan,Tudor Ciuleanu,Pauline Wimberger,Alexander Schmittel,Barbara Schmalfeldt,Alexander Burges,Carsten Bokemeyer,Horst Lindhofer,Angelika Lahr,Simon L. Parsons +19 more
TL;DR: Catumaxomab showed a clear clinical benefit in patients with malignant ascites secondary to epithelial cancers, especially gastric cancer, with an acceptable safety profile.
Journal ArticleDOI
Surgery in Recurrent Ovarian Cancer: The Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) DESKTOP OVAR Trial
Philipp Harter,Andreas du Bois,M. Hahmann,Annette Hasenburg,Alexander Burges,Sibylle Loibl,M. Gropp,Jens Huober,Daniel Fink,W. Schröder,Karsten Muenstedt,Barbara Schmalfeldt,Guenter Emons,Jacobus Pfisterer,K. Wollschlaeger,H. G. Meerpohl,G. P. Breitbach,Berno Tanner,Jalid Sehouli +18 more
TL;DR: Only complete resection was associated with prolonged survival in recurrent ovarian cancer and the identified criteria panel will be verified in a prospective trial evaluating whether it will render a useful tool for selecting the right patients for cytoreductive surgery in recurrent Ovarian cancer.
Journal ArticleDOI
A Randomized Trial of Lymphadenectomy in Patients with Advanced Ovarian Neoplasms
Philipp Harter,Jalid Sehouli,Domenica Lorusso,Alexander Reuss,Ignace Vergote,Christian Marth,Jae Weon Kim,Francesco Raspagliesi,Björn Lampe,Giovanni Aletti,Werner Meier,David Cibula,Alexander Mustea,Sven Mahner,IB Runnebaum,B Schmalfeldt,Alexander Burges,Rainer Kimmig,Giovanni Scambia,Stefano Greggi,Felix Hilpert,Annette Hasenburg,Peter Hillemanns,Giorgio Giorda,Ingo von Leffern,Carmen Schade-Brittinger,Uwe Wagner,Andreas du Bois +27 more
TL;DR: Systematic pelvic and paraaortic lymphadenectomy in patients with advanced ovarian cancer who had undergone intraabdominal macroscopically complete resection and had normal lymph nodes both before and during surgery was not associated with longer overall or progression‐free survival and was associated with a higher incidence of postoperative complications.
Journal ArticleDOI
Effective relief of malignant ascites in patients with advanced ovarian cancer by a trifunctional anti-EpCAM x anti-CD3 antibody: a phase I/II study.
Alexander Burges,Pauline Wimberger,Carolin Kümper,Vera Gorbounova,Harald Sommer,Barbara Schmalfeldt,Jacobus Pfisterer,Michail Lichinitser,Anatoliy Makhson,Vladimir Moiseyenko,Angelika Lahr,Elisabeth Schulze,Michael Jäger,Michael A. Ströhlein,Markus M. Heiss,Thomas Gottwald,Horst Lindhofer,Rainer Kimmig +17 more
TL;DR: It is suggested that catumaxomab is a promising treatment option in ovarian cancer patients with malignant ascites because it prevented the accumulation of ascites and efficiently eliminated tumor cells with an acceptable safety profile.