Showing papers by "Alexander N. Glazer published in 2003"
01 Jan 2003
TL;DR: Fluorescence resonance energy transfer technology has done much to enhance DNA sequencing capabilities and the Human Genome Project and should be equally valuable for the analysis of PCR fragments, restriction fragments, single nucleotide polymor-phisms, and microsatellites in research, pharmaceutical, and health care diagnostic applications.
Abstract: Fluorescence resonance energy transfer technology has done much to enhance DNA sequencing capabilities and the Human Genome Project. The enhanced emission intensities and improved spectral purity provided by ET primers and terminators have led to a major improvement in the performance of automated DNA sequencers. Fluorescent ET dye-labels should be equally valuable for the analysis of PCR fragments, restriction fragments, single nucleotide polymor-phisms, and microsatellites in research, pharmaceutical, and health care diagnostic applications.