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Alexandra Stolz
Researcher at Goethe University Frankfurt
Publications - 45
Citations - 5589
Alexandra Stolz is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Autophagy & Endoplasmic reticulum. The author has an hindex of 23, co-authored 38 publications receiving 4347 citations. Previous affiliations of Alexandra Stolz include Structural Genomics Consortium & Genentech.
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Journal ArticleDOI
Basic and applied aspects in the microbial degradation of azo dyes
TL;DR: Several (laboratory-scale) continuous anaerobic/aerobic processes for the treatment of wastewaters containing azo dyes have recently been described.
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Cargo recognition and trafficking in selective autophagy
TL;DR: The current view on how cargo selection and transport are achieved during selective autophagy is discussed, and molecular mechanisms that are congruent between autophagosomal membranes and vesicle trafficking pathways are pointed out.
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Regulation of endoplasmic reticulum turnover by selective autophagy
Aliaksandr Khaminets,Theresa Heinrich,Muriel Mari,Paolo Grumati,Antje K. Huebner,Masato Akutsu,Lutz Liebmann,Alexandra Stolz,Sandor Nietzsche,Nicole Koch,Mario Mauthe,Istvan Katona,Britta Qualmann,Joachim Weis,Fulvio Reggiori,Ingo Kurth,Christian A. Hübner,Ivan Dikic +17 more
TL;DR: Severe disruption of Fam134b in mice causes expansion of the ER, inhibits ER turnover, sensitizes cells to stress-induced apoptotic cell death and leads to degeneration of sensory neurons, so selective ER-phagy via FAM134 proteins is indispensable for mammalian cell homeostasis and controls ER morphology and turnover in mice and humans.
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Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
Benjamin Richter,Danielle A. Sliter,Lina Herhaus,Alexandra Stolz,Chunxin Wang,Petra Beli,Gabriele Zaffagnini,Philipp Wild,Sascha Martens,Sebastian Wagner,Richard J. Youle,Ivan Dikic,Ivan Dikic +12 more
TL;DR: Quantitative proteomics shows that Tank-binding kinase 1 (TBK1) phosphorylates all four receptors on several autophagy-relevant sites, including the ubiquitin- and LC3-binding domains of OPTN and p62/SQSTM1 as well as the SKICH domains of NDP52 and TAX1BP1.
Journal ArticleDOI
Autophagy in major human diseases
Daniel J. Klionsky,Giulia Petroni,Ravi K. Amaravadi,Eric H. Baehrecke,Andrea Ballabio,Andrea Ballabio,Patricia Boya,José Manuel Bravo-San Pedro,Ken Cadwell,Francesco Cecconi,Francesco Cecconi,Augustine M.K. Choi,Augustine M.K. Choi,Mary E. Choi,Mary E. Choi,Charleen T. Chu,Patrice Codogno,Patrice Codogno,María Isabel Colombo,Ana Maria Cuervo,Vojo Deretic,Ivan Dikic,Zvulun Elazar,Eeva-Liisa Eskelinen,Gian Maria Fimia,David A. Gewirtz,Douglas R. Green,Malene Hansen,Marja Jäättelä,Terje Johansen,Gábor Juhász,Vassiliki Karantza,Claudine Kraft,Guido Kroemer,Nicholas T. Ktistakis,Sharad Kumar,Sharad Kumar,Carlos López-Otín,Kay F. Macleod,Frank Madeo,Jennifer Martinez,Alicia Meléndez,Alicia Meléndez,Noboru Mizushima,Christian Münz,Josef M. Penninger,Josef M. Penninger,Rushika M. Perera,Mauro Piacentini,Mauro Piacentini,Fulvio Reggiori,David C. Rubinsztein,Kevin M. Ryan,Junichi Sadoshima,Laura Santambrogio,Luca Scorrano,Hans-Uwe Simon,Hans-Uwe Simon,Anna Katharina Simon,Anne Simonsen,Anne Simonsen,Alexandra Stolz,Nektarios Tavernarakis,Nektarios Tavernarakis,Sharon A. Tooze,Tamotsu Yoshimori,Junying Yuan,Junying Yuan,Zhenyu Yue,Qing Zhong,Lorenzo Galluzzi,Federico Pietrocola +71 more
TL;DR: In this paper, preclinical data linking autophagy dysfunction to the pathogenesis of major human disorders including cancer as well as cardiovascular, neurodegenerative, metabolic, pulmonary, renal, infectious, musculoskeletal, and ocular disorders.