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Alexandros D. Tselepis
Researcher at University of Ioannina
Publications - 281
Citations - 9407
Alexandros D. Tselepis is an academic researcher from University of Ioannina. The author has contributed to research in topics: Lipoprotein & Cholesterol. The author has an hindex of 49, co-authored 263 publications receiving 8546 citations.
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Journal ArticleDOI
Oxidative stress is progressively enhanced with advancing stages of CKD.
Evangelia Dounousi,Eleni C. Papavasiliou,Areti Makedou,Kyriakos Ioannou,Konstantinos P. Katopodis,Alexandros D. Tselepis,Kostas C. Siamopoulos,Dimitrios Tsakiris +7 more
TL;DR: Oxidative stress appears to increase as CKD progresses and correlates significantly with level of renal function, and increased TAS seems to be dependent on several confounding variables, including increased uric acid levels, and therefore does not seem to be a reliable method for assessing the antioxidant capacity of patients with CKD.
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Inflammation, bioactive lipids and atherosclerosis: potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase
TL;DR: The main structural and catalytic features of plasma PAF-AH are focused on, on the association of the enzyme with distinct lipoprotein particle subspecies, on its cellular sources, and finally on the potential significance of this lipop Protein-associated PLA(2) in cardiovascular disease.
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Atherogenic lipid profile is a feature characteristic of patients with early rheumatoid arthritis: effect of early treatment – a prospective, controlled study
A N Georgiadis,Eleni C. Papavasiliou,Evangelia S. Lourida,Yannis Alamanos,Christina Kostara,Alexandros D. Tselepis,Alexandros A. Drosos +6 more
TL;DR: ERA patients are characterized by an atherogenic lipid profile, which improves after therapy, and early immuno-intervention to control disease activity may reduce the risk of the atherosclerotic process and cardiovascular events in ERA patients.
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PAF-Degrading Acetylhydrolase Is Preferentially Associated With Dense LDL and VHDL-1 in Human Plasma Catalytic Characteristics and Relation to the Monocyte-Derived Enzyme
TL;DR: The distribution, catalytic characteristics, and transfer of acetylhydrolase activity among plasma lipoprotein subspecies separated by isopycnic density gradient ultracentrifugation are examined and the possibility that the plasma enzyme may be partially derived from adherent monocytes has also been evaluated.
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The use of statins alone, or in combination with pioglitazone and other drugs, for the treatment of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and related cardiovascular risk. An Expert Panel Statement.
Vasilios G. Athyros,Theodore K. Alexandrides,Helen Bilianou,Evangelos Cholongitas,Michael Doumas,Emmanuel S. Ganotakis,John A. Goudevenos,M.S. Elisaf,Georgios Germanidis,Olga Giouleme,Asterios Karagiannis,Charalambos Karvounis,Niki Katsiki,Vasilios Kotsis,Jannis Kountouras,Evangelos Liberopoulos,Christos Pitsavos,Stergios A. Polyzos,Loukianos S. Rallidis,Dimitrios J. Richter,Apostolos Tsapas,Alexandros D. Tselepis,Konstantinos Tsioufis,Konstantinos Tziomalos,Themistoklis Tzotzas,Themistoklis G. Vasiliadis,Charalambos Vlachopoulos,Dimitri P. Mikhailidis,Christos S. Mantzoros +28 more
TL;DR: Physicians should consider using a PPARgamma agonist, such as pioglitazone, or statin use in those with NAFLD/NASH at high CVD or HCC risk, alone and/or preferably in combination with each other or with ezetimibe, for the primary or secondary prevention of CVD.