Author
Alexey V. Rukavishnikov
Bio: Alexey V. Rukavishnikov is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Singularity & Carene. The author has an hindex of 5, co-authored 18 publications receiving 97 citations.
Papers
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36 citations
TL;DR: The weighted analogue of the Ladyzhenskaya–Babuska–Brezzi condition is proved and a new weighted finite element method is constructed that shows the efficiency of the method.
28 citations
TL;DR: The results of computational simulations have shown that the convergence rate of the approximate solution by weighted FEM to the exact solution does not depend on the value of the internal corner ω and equals O ( h ) in the norm of a space W 2, ν 1 ( Ω ) .
Abstract: In the paper, a new numerical approach for the rotation form of the Oseen system in a polygon Ω with an internal corner ω greater than 180 ∘ on its boundary is presented. The results of computational simulations have shown that the convergence rate of the approximate solution (velocity field) by weighted FEM to the exact solution does not depend on the value of the internal corner ω and equals O ( h ) in the norm of a space W 2 , ν 1 ( Ω ) .
12 citations
01 Jan 2018-Bulletin of the South Ural State University. Series "Mathematical Modelling, Programming and Computer Software
9 citations
TL;DR: In this paper, the 2-acetylcyclopent-1-en-1ylamine type enaminones from terpenic compounds are described and the preparation of enaminone from terpene compounds is described.
7 citations
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TL;DR: Amides of GL and conjugates of GL with two amino acid residues and a free 30-COOH function presented up to 70-fold increased activity against SARS-CoV but also increased cytotoxicity resulting in decreased selectivity index.
Abstract: Glycyrrhizin (GL) was shown to inhibit SARS-coronavirus (SARS-CoV) replication in vitro. Here the anti-SARS-CoV activity of 15 GL derivatives was tested. The introduction of 2-acetamido-beta-d-glucopyranosylamine into the glycoside chain of GL resulted in 10-fold increased anti-SARS-CoV activity compared to GL. Amides of GL and conjugates of GL with two amino acid residues and a free 30-COOH function presented up to 70-fold increased activity against SARS-CoV but also increased cytotoxicity resulting in decreased selectivity index.
323 citations
TL;DR: One-pot synthesis of 2-(arylthio)arylcyanamides is accomplished using cheap and air-stable CuSO(4) x 5 H(2)O as a catalyst by domino intra- and intermolecular C-S cross-coupling reactions of 2"-iodoaryl)thioureas with aryl iodides under ligand-free conditions.
59 citations
TL;DR: A review of recent advances in the X-CN (X=N, S, O) bond formation can be found in this article, where the outlooks for the future are discussed.
Abstract: The cyano moiety is a common and important functional group that exists in a myriad of medicinal molecules and natural products. Moreover, nitriles serve as versatile precursors that can readily be converted into diverse functional groups as well as the nitrogen-containing cyclic molecules. As a result, cyanation has become a significant type of transformation in organic chemistry. However, in comparison with the well-developed C-cyanation, few works have been reported dealing with the N-, S- and O-cyanation processes. Apart from the classical von Braun reaction, chemists have developed a number of methods with various cyanating reagents to achieve such X-cyanations (X=N, S, O). In this review, recent advances (especially those after 2000) in the X–CN (X=N, S, O) bond formation are summarized with discussion and the outlooks are also listed.
57 citations
TL;DR: In this paper, a review briefly discusses the known methods for the preparation of substituted cyanamides, their typical transformations, and some aspects of practical applications of these compounds in medicine, various branches of industry, and agriculture.
Abstract: The review briefly discusses the known methods for the preparation of substituted cyanamides, their typical transformations, and some aspects of practical applications of these compounds in medicine, various branches of industry, and agriculture.
54 citations
TL;DR: A facile and general synthesis of various N-substituted cyanamides was accomplished by the Tiemann rearrangement of amidoximes with benzenesulfonyl chlorides (TsCl or o-NsCl) and DIPEA.
50 citations