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Alfons Meindl

Researcher at Ludwig Maximilian University of Munich

Publications -  315
Citations -  33718

Alfons Meindl is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 83, co-authored 306 publications receiving 29202 citations. Previous affiliations of Alfons Meindl include Peter MacCallum Cancer Centre & Technische Universität München.

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The DNA sequence of the human X chromosome

Mark T. Ross, +282 more
- 17 Mar 2005 - 
TL;DR: This analysis illustrates the autosomal origin of the mammalian sex chromosomes, the stepwise process that led to the progressive loss of recombination between X and Y, and the extent of subsequent degradation of the Y chromosome.
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Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni J. Vilhjálmsson, +394 more
- 01 Oct 2015 - 
TL;DR: LDpred is introduced, a method that infers the posterior mean effect size of each marker by using a prior on effect sizes and LD information from an external reference panel, and outperforms the approach of pruning followed by thresholding, particularly at large sample sizes.
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Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Kyriaki Michailidou, +220 more
- 01 Apr 2013 - 
TL;DR: A meta-analysis of 9 genome-wide association studies, including 10,052 breast cancer cases and 12,575 controls of European ancestry, and identified 29,807 SNPs for further genotyping suggests that more than 1,000 additional loci are involved in breast cancer susceptibility.
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Association analysis identifies 65 new breast cancer risk loci

Kyriaki Michailidou, +396 more
- 02 Nov 2017 - 
TL;DR: A genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of East Asian ancestry finds that heritability of Breast cancer due to all single-nucleotide polymorphisms in regulatory features was 2–5-fold enriched relative to the genome- wide average.
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A gene (PEX) with homologies to endopeptidases is mutated in patients with X–linked hypophosphatemic rickets

Fiona Francis, +28 more
- 04 May 1995 - 
TL;DR: Intragenic non–overlapping deletions from four different families and three mutations have been detected in HYP patients, which suggest that the PEX gene is involved in the HYP disorder.