Ali H. Bahkali

Bio: Ali H. Bahkali is an academic researcher from King Saud University. The author has contributed to research in topics: Dothideomycetes & Pleosporales. The author has an hindex of 50, co-authored 287 publications receiving 9411 citations. Previous affiliations of Ali H. Bahkali include Yeungnam University & Landcare Research.

Biological control of Sclerotinia sclerotiorum in beans with antagonistic microorganisms under greenhouse conditions

Abstract: The effects of the mycoparasites Coniothyrium minitans and Trichoderma harzianum, Trichoderma viride, Trichoderma hamatum, Gliocladium virens, Gliocladium roseum, Pseudomonas fluorescens, Streptomyces griseoviridis and Bacillus subtilis on the suppression of bean white rot caused by Sclerotinia sclerotiorum were evaluated in vivo during 2013. Results showed that soil drenching with C. minitans, T. viride and T. hamatum significantly suppressed the white rot disease incidence with 90% survival plants. In case of mixture, antagonistic fungi and antagonistic bacteria, the mixtures of T. hamatum+S. griseoviridis and C. minitans + S. griseoviridis completely inhibited the disease incidence that produced 100% survival plants when compared to controls.

Novel Quinoline-Derived Chemosensors: Synthesis, Anion Recognition, Spectroscopic and Computational Study

Abstract: Fluorescent-small molecules offer an excellent source of chemosensors when optimized for detection of anions with sensitivity and selectivity, low-cost and robust synthesis. In the present study we synthesized new quinoline-based...

Significance of Immune Status of SARS-CoV-2 Infected Patients in Determining the Efficacy of Therapeutic Interventions

Abstract: Coronavirus disease 2019 (COVID-19) is now being investigated for its distinctive patterns in the course of disease development which can be indicated with miscellaneous immune responses in infected individuals. Besides this series of investigations on the pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), significant fundamental immunological and physiological processes are indispensable to address clinical markers of COVID-19 disease and essential to identify or design effective therapeutics. Recent developments in the literature suggest that deficiency of type I interferon (IFN) in serum samples can be used to represent a severe progression of COVID-19 disease and can be used as the basis to develop combined immunotherapeutic strategies. Precise control over inflammatory response is a significant aspect of targeting viral infections. This account presents a brief review of the pathophysiological characteristics of the SARS-CoV-2 virus and the understanding of the immune status of infected patients. We further discuss the immune system’s interaction with the SARS-CoV-2 virus and their subsequent involvement of dysfunctional immune responses during the progression of the disease. Finally, we highlight some of the implications of the different approaches applicable in developing promising therapeutic interventions that redirect immunoregulation and viral infection.

Towards a natural classification of Dothideomycetes: 8. The genera Cocconia, Dianesea, Endococcus and Lineostroma

Abstract: The generic types of four genera with unclear placement in Dothideomycetes were re-examined. These genera were hitherto poorly illustrated or described. The type specimens of Cocconia ( C. palmae ), Dianesea ( D. palmae ), Endococcus ( E. rugulosus ) and Lineostroma ( L. banksiae ), were re-examined in order to determine their familial and higher level placements, according to their morphology and based on modern taxonomic concepts. A resume of the history along with descriptions and illustrations of these genera are provided. Endococcus and Lineostroma are placed in families Lichenotheliaceae and Didymosphaeriaceae, respectively, based on morphology. The placement of Cocconia within Parmulariaceae is confirmed. Dianesea is retained in Dothideomycetes genera incertae sedis as it is not typical of any existing family of Dothideomycetes . Fresh collections of these genera are needed for further study, so that they can be epitypified and molecular data is needed to validate their phylogeny and natural classification.

A new species

Abstract: We redescribe the only previously known species of Myrsidea from bulbuls, M. pycnonoti Eichler. Sixteen new species are described; they and their type hosts are: M. phillipsi ex Pycnonotus goiavier goiavier (Scopoli), M. gieferi ex P. goiavier suluensis Mearns, M. kulpai ex P. flavescens Blyth, M. finlaysoni ex P. finlaysoni Strickland, M. kathleenae ex P. cafer (L.), M. warwicki ex Ixos philippinus (J. R. Forster), M. mcclurei ex Microscelis amaurotis (Temminck), M. zeylanici ex P. zeylanicus (Gmelin), M. plumosi ex P. plumosus Blyth, M. eutiloti ex P. eutilotus (Jardine and Selby), M. adamsae ex P. urostictus (Salvadori), M. ochracei ex Criniger ochraceus F. Moore, M. borbonici ex Hypsipetes borbonicus (J. R. Forster), M. johnsoni ex P. atriceps (Temminck), M. palmai ex C. ochraceus, and M. claytoni ex P. eutilotus. A key is provided for the identification of these 17 species.

Ab initio calculation of vibrational absorption and circular dichroism spectra using density functional force fields

Abstract: : The unpolarized absorption and circular dichroism spectra of the fundamental vibrational transitions of the chiral molecule, 4-methyl-2-oxetanone, are calculated ab initio. Harmonic force fields are obtained using Density Functional Theory (DFT), MP2, and SCF methodologies and a 5S4P2D/3S2P (TZ2P) basis set. DFT calculations use the Local Spin Density Approximation (LSDA), BLYP, and Becke3LYP (B3LYP) density functionals. Mid-IR spectra predicted using LSDA, BLYP, and B3LYP force fields are of significantly different quality, the B3LYP force field yielding spectra in clearly superior, and overall excellent, agreement with experiment. The MP2 force field yields spectra in slightly worse agreement with experiment than the B3LYP force field. The SCF force field yields spectra in poor agreement with experiment.The basis set dependence of B3LYP force fields is also explored: the 6-31G* and TZ2P basis sets give very similar results while the 3-21G basis set yields spectra in substantially worse agreements with experiment. jg

A European Database of Fusarium graminearum and F. culmorum Trichothecene Genotypes

Abstract: Fusarium species, particularly Fusarium graminearum and F. culmorum, are the main cause of trichothecene type B contamination in cereals. Data on the distribution of Fusarium trichothecene genotypes in cereals in Europe are scattered in time and space. Furthermore, a common core set of related variables (sampling method, host cultivar, previous crop, etc.) that would allow more effective analysis of factors influencing the spatial and temporal population distribution, is lacking. Consequently, based on the available data, it is difficult to identify factors influencing chemotype distribution and spread at the European level. Here we describe the results of a collaborative integrated work which aims (1) to characterize the trichothecene genotypes of strains from three Fusarium species, collected over the period 2000–2013 and (2) to enhance the standardization of epidemiological data collection. Information on host plant, country of origin, sampling location, year of sampling and previous crop of 1147 F. graminearum, 479 F. culmorum, and 3 F. cortaderiae strains obtained from 17 European countries was compiled and a map of trichothecene type B genotype distribution was plotted for each species. All information on the strains was collected in a freely accessible and updatable database (www.catalogueeu.luxmcc.lu), which will serve as a starting point for epidemiological analysis of potential spatial and temporal trichothecene genotype shifts in Europe. The analysis of the currently available European dataset showed that in F. graminearum, the predominant genotype was 15-acetyldeoxynivalenol (15-ADON) (82.9%), followed by 3-acetyldeoxynivalenol (3-ADON) (13.6%), and nivalenol (NIV) (3.5%). In F. culmorum, the prevalent genotype was 3-ADON (59.9%), while the NIV genotype accounted for the remaining 40.1%. Both, geographical and temporal patterns of trichothecene genotypes distribution were identified.