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Alkis Togias
Researcher at National Institutes of Health
Publications - 317
Citations - 27723
Alkis Togias is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Asthma & Allergy. The author has an hindex of 74, co-authored 288 publications receiving 24567 citations. Previous affiliations of Alkis Togias include University of Genoa & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)
Jean Bousquet,N. Khaltaev,Alvaro A. Cruz,Judah A. Denburg,W. J. Fokkens,Alkis Togias,T. Zuberbier,Carlos E. Baena-Cagnani,Giorgio Walter Canonica,C. van Weel,Ioana Agache,Nadia Aït-Khaled,Claus Bachert,Michael S. Blaiss,Sergio Bonini,L.-P. Boulet,Philippe-Jean Bousquet,Paulo Augusto Moreira Camargos,K-H. Carlsen,Y. Z. Chen,Adnan Custovic,Ronald Dahl,Pascal Demoly,H. Douagui,Stephen R. Durham,R. Gerth van Wijk,O. Kalayci,Michael A. Kaliner,You Young Kim,Marek L. Kowalski,Piotr Kuna,L. T. T. Le,Catherine Lemière,Jing Li,Richard F. Lockey,S. Mavale-Manuel,Eli O. Meltzer,Y. Mohammad,J Mullol,Robert M. Naclerio,Robyn E O'Hehir,K. Ohta,S. Ouedraogo,S. Palkonen,Nikolaos G. Papadopoulos,Gianni Passalacqua,Ruby Pawankar,Todor A. Popov,Klaus F. Rabe,J Rosado-Pinto,G. K. Scadding,F. E. R. Simons,Elina Toskala,E. Valovirta,P. Van Cauwenberge,De Yun Wang,Magnus Wickman,Barbara P. Yawn,Arzu Yorgancioglu,Osman M. Yusuf,H. J. Zar,Isabella Annesi-Maesano,E.D. Bateman,A. Ben Kheder,Daniel A. Boakye,J. Bouchard,Peter Burney,William W. Busse,Moira Chan-Yeung,Niels H. Chavannes,A.G. Chuchalin,William K. Dolen,R. Emuzyte,Lawrence Grouse,Marc Humbert,C. M. Jackson,Sebastian L. Johnston,Paul K. Keith,James P. Kemp,J. M. Klossek,Désirée Larenas-Linnemann,Brian J. Lipworth,Jean-Luc Malo,Gailen D. Marshall,Charles K. Naspitz,K. Nekam,Bodo Niggemann,Ewa Nizankowska-Mogilnicka,Yoshitaka Okamoto,M. P. Orru,Paul Potter,David Price,Stuart W. Stoloff,Olivier Vandenplas,Giovanni Viegi,Dennis M. Williams +95 more
TL;DR: The ARIA guidelines for the management of allergic rhinitis and asthma are similar in both the 1999 ARIA workshop report and the 2008 Update as discussed by the authors, but the GRADE approach is not yet available.
Journal ArticleDOI
Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines—2016 revision
Jan Brozek,Jean Bousquet,Ioana Agache,Arnav Agarwal,Claus Bachert,Sinthia Bosnic-Anticevich,Romina Brignardello-Petersen,G. Walter Canonica,Thomas B. Casale,Niels H. Chavannes,Jaime Correia de Sousa,Alvaro A. Cruz,Carlos A. Cuello-Garcia,Pascal Demoly,Mark S. Dykewicz,Itziar Etxeandia-Ikobaltzeta,Ivan D. Florez,Wytske Fokkens,João Fonseca,Peter Hellings,Ludger Klimek,Sergio Kowalski,Piotr Kuna,Kaja-Triin Laisaar,Désirée Larenas-Linnemann,Karin C. Lødrup Carlsen,Peter J. Manning,Eli O. Meltzer,Joaquim Mullol,Antonella Muraro,Robyn E O'Hehir,Ken Ohta,Petr Panzner,Nikolaos G. Papadopoulos,Hae-Sim Park,Gianni Passalacqua,Ruby Pawankar,David Price,John J. Riva,Yetiani Roldan,Dermot Ryan,Behnam Sadeghirad,Bolesław Samoliński,Peter Schmid-Grendelmeier,Aziz Sheikh,Alkis Togias,Antonio Valero,Arunas Valiulis,Erkka Valovirta,Matthew Ventresca,Dana Wallace,Susan Waserman,Magnus Wickman,Wojtek Wiercioch,Juan José Yepes-Nuñez,Luo Zhang,Yuan Zhang,Mihaela Zidarn,Torsten Zuberbier,Holger J. Schünemann +59 more
TL;DR: The 2016 revision of the ARIA guidelines provides both updated and new recommendations about the pharmacologic treatment of AR, addressing the relative merits of using oral H1‐antihistamines, intranasal H1-antihistsamines, IntranasAL corticosteroids, and leukotriene receptor antagonists either alone or in combination.
Journal ArticleDOI
Rhinosinusitis: Establishing definitions for clinical research and patient care
Eli O. Meltzer,Daniel L. Hamilos,James A. Hadley,Donald C. Lanza,Bradley F. Marple,Richard A. Nicklas,Claus Bachert,James N. Baraniuk,Fuad M. Baroody,Michael S. Benninger,Itzhak Brook,Badrul A. Chowdhury,Howard M. Druce,Stephen R. Durham,Berrylin J. Ferguson,Jack M. Gwaltney,Michael A. Kaliner,David W. Kennedy,Valerie J. Lund,Robert M. Naclerio,Ruby Pawankar,Jay F. Piccirillo,Patricia E. W. Rohane,Ronald A. Simon,Raymond G. Slavin,Alkis Togias,Ellen R. Wald,S. James Zinreich +27 more
TL;DR: An expert panel from multiple disciplines developed definitions for rhinosinusitis and outlined strategies for design of clinical trials and reached consensus on definitions and strategies for clinical research on acute presumed bacterial rhinosineitis, chronic rhinosinitis with polyposis, and classic allergic fungal rhinusitis.
Journal Article
Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody.
Donald W. MacGlashan,Bruce S. Bochner,Daniel C. Adelman,Paula M. Jardieu,Alkis Togias,Jane McKenzie-White,Sherry A. Sterbinsky,Robert G. Hamilton,Lawrence M. Lichtenstein +8 more
TL;DR: The responsiveness of the cells to IgE-mediated stimulation using anti-IgE Ab was marginally decreased while the response of the same cells to stimulation with dust mite Ag, Dermatophagoides farinae, was reduced by approximately 90%.
Journal ArticleDOI
Randomized Trial of Omalizumab (Anti-IgE) for Asthma in Inner-City Children
William W. Busse,Wayne J. Morgan,Peter J. Gergen,Herman Mitchell,James E. Gern,Andrew H. Liu,Rebecca S. Gruchalla,Meyer Kattan,Stephen J. Teach,Jacqueline A. Pongracic,James F. Chmiel,Suzanne Steinbach,Agustin Calatroni,Alkis Togias,Katherine M. Thompson,Stanley J. Szefler,Christine A. Sorkness +16 more
TL;DR: When added to a regimen of guidelines-based therapy for inner-city children, adolescents, and young adults, omalizumab further improved asthma control, nearly eliminated seasonal peaks in exacerbations, and reduced the need for other medications to control asthma.