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Allen J. M. Huxley

Other affiliations: Queen's University
Bio: Allen J. M. Huxley is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: Photoinduced electron transfer & Triode. The author has an hindex of 8, co-authored 9 publications receiving 6599 citations. Previous affiliations of Allen J. M. Huxley include Queen's University.

Papers
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Journal ArticleDOI
TL;DR: In this paper, two leading designs of fluorescent sensors are combined to yield the novel hybrid system of the ‘Fluorophore-Receptor1-Spacer-Recept2’ format.

69 citations

Journal ArticleDOI
TL;DR: The photophysical concepts of metal-centred (MC) excited states, metal to ligand charge transfer (MLCT), photoinduced electron transfer (PET) processes and electronic energy transfer (EET) processes are all being exploited during these signalling operations.

65 citations

Journal ArticleDOI
TL;DR: A simple alcohol-ketone redox interconversion which switches a macrocycle between a large or small cavity, with erect aromatic walls which create a deep hydrophobic space or with collapsed walls respectively is reported.
Abstract: Molecular-logic based computation (MLBC) has grown by accumulating many examples of combinational logic gates and a few sequential variants. In spite of many inspirations being available in biology, there are virtually no examples of MLBC in chemistry where sequential and combinational operations are integrated. Here we report a simple alcohol-ketone redox interconversion which switches a macrocycle between a large or small cavity, with erect aromatic walls which create a deep hydrophobic space or with collapsed walls respectively. Small aromatic guests can be captured or released in an all or none manner upon chemical command. During capture, the fluorescence of the alcohol macrocycle is quenched via fluorescent photoinduced electron transfer switching, meaning that its occupancy state is self-indicated. This represents a chemically-driven RS Flip-Flop, one of whose outputs is fed into an INHIBIT gate. Processing of outputs from memory stores is seen in the injection of packaged neurotransmitters into synaptic clefts for onward neural signalling. Overall, capture-release phenomena from discrete supermolecules now have a Boolean basis.

40 citations


Cited by
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Journal ArticleDOI
TL;DR: Anion recognition chemistry has grown from its beginnings with positively charged ammonium cryptand receptors for halide binding to a plethora of charged and neutral, cyclic and acyclic, inorganic and organic supramolecular host systems for the selective complexation, detection, and separation of anionic guest species.
Abstract: Anion recognition chemistry has grown from its beginnings in the late 1960s with positively charged ammonium cryptand receptors for halide binding to, at the end of the millennium, a plethora of charged and neutral, cyclic and acyclic, inorganic and organic supramolecular host systems for the selective complexation, detection, and separation of anionic guest species. Solvation effects and pH values have been shown to play crucial roles in the overall anion recognition process. More recent developments include exciting advances in anion-templated syntheses and directed self-assembly, ion-pair recognition, and the function of anions in supramolecular catalysis.

3,145 citations

Journal ArticleDOI
TL;DR: The Bodipy family, first developed as luminescent tags and laser dyes, has become a cornerstone for these new applications and the near future looks extremely bright for "porphyrin's little sister".
Abstract: The world of organic luminophores has been confined for a long time to fairly standard biological labeling applications and to certain analytical tests. Recently, however, the field has undergone a major change of direction, driven by the dual needs to develop novel organic electronic materials and to fuel the rapidly emerging nanotechnologies. Among the many diverse fluorescent molecules, the Bodipy family, first developed as luminescent tags and laser dyes, has become a cornerstone for these new applications. The near future looks extremely bright for "porphyrin's little sister".

2,705 citations