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Alon Savidor
Researcher at Weizmann Institute of Science
Publications - 46
Citations - 4863
Alon Savidor is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 20, co-authored 39 publications receiving 3980 citations. Previous affiliations of Alon Savidor include University of Tennessee & Oak Ridge National Laboratory.
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Journal ArticleDOI
Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans.
Brian J. Haas,Sophien Kamoun,Sophien Kamoun,Michael C. Zody,Michael C. Zody,Rays H. Y. Jiang,Rays H. Y. Jiang,Robert E. Handsaker,Liliana M. Cano,Manfred Grabherr,Chinnappa D. Kodira,Chinnappa D. Kodira,Sylvain Raffaele,Trudy Torto-Alalibo,Trudy Torto-Alalibo,Tolga O. Bozkurt,Audrey M. V. Ah-Fong,Lucia Alvarado,Vicky L. Anderson,Miles R. Armstrong,Anna O. Avrova,Laura Baxter,Jim Beynon,Petra C. Boevink,Stephanie R. Bollmann,Jorunn I. B. Bos,Vincent Bulone,Guohong Cai,Cahid Cakir,James C. Carrington,Megan Chawner,Lucio Conti,Stefano Costanzo,Richard Ewan,Noah Fahlgren,Michael A. Fischbach,Johanna Fugelstad,Eleanor M. Gilroy,Sante Gnerre,Pamela J. Green,Laura J. Grenville-Briggs,John Griffith,Niklaus J. Grünwald,Karolyn Horn,Neil R. Horner,Chia-Hui Hu,Edgar Huitema,Dong-Hoon Jeong,Alexandra M. E. Jones,Jonathan D. G. Jones,Richard W. Jones,Elinor K. Karlsson,Sridhara G. Kunjeti,Kurt Lamour,Zhenyu Liu,Li-Jun Ma,Dan MacLean,Marcus C. Chibucos,Hayes McDonald,Jessica McWalters,Harold J. G. Meijer,William Morgan,Paul Morris,Carol A. Munro,Keith O'Neill,Keith O'Neill,Manuel D. Ospina-Giraldo,Andrés Pinzón,Leighton Pritchard,Bernard H Ramsahoye,Qinghu Ren,Silvia Restrepo,Sourav Roy,Ari Sadanandom,Alon Savidor,Sebastian Schornack,David C. Schwartz,Ulrike Schumann,Ben Schwessinger,Lauren Seyer,Ted Sharpe,Cristina Silvar,Jing Song,David J. Studholme,Sean M. Sykes,Marco Thines,Marco Thines,Peter J. I. van de Vondervoort,Vipaporn Phuntumart,Stephan Wawra,R. Weide,Joe Win,Carolyn A. Young,Shiguo Zhou,William E. Fry,Blake C. Meyers,Pieter van West,Jean B. Ristaino,Francine Govers,Paul R. J. Birch,Stephen C. Whisson,Howard S. Judelson,Chad Nusbaum +102 more
TL;DR: The sequence of the P. infestans genome is reported, which at ∼240 megabases (Mb) is by far the largest and most complex genome sequenced so far in the chromalveolates and probably plays a crucial part in the rapid adaptability of the pathogen to host plants and underpins its evolutionary potential.
Journal ArticleDOI
Phytophthora Genome Sequences Uncover Evolutionary Origins and Mechanisms of Pathogenesis
Brett M. Tyler,Sucheta Tripathy,Xuemin Zhang,Paramvir S. Dehal,Paramvir S. Dehal,Rays H. Y. Jiang,Rays H. Y. Jiang,Andrea Aerts,Andrea Aerts,Felipe D. Arredondo,Laura Baxter,Douda Bensasson,Douda Bensasson,Douda Bensasson,Jim Beynon,Jarrod Chapman,Jarrod Chapman,Jarrod Chapman,C. M. B. Damasceno,Anne E. Dorrance,Daolong Dou,Allan W. Dickerman,Inna Dubchak,Inna Dubchak,Matteo Garbelotto,Mark Gijzen,Stuart G. Gordon,Francine Govers,Niklaus J. Grünwald,Wayne Huang,Wayne Huang,Kelly Ivors,Kelly Ivors,Richard W. Jones,Sophien Kamoun,Konstantinos Krampis,Kurt Lamour,Mi-Kyung Lee,W. Hayes McDonald,MoÌnica Medina,Harold J. G. Meijer,Eric K. Nordberg,Donald J. Maclean,Manuel D. Ospina-Giraldo,Paul Morris,Vipaporn Phuntumart,Nicholas H. Putnam,Nicholas H. Putnam,Sam Rash,Sam Rash,Jocelyn K. C. Rose,Yasuko Sakihama,Asaf Salamov,Asaf Salamov,Alon Savidor,Chantel F. Scheuring,Brian M. Smith,Bruno W. S. Sobral,Astrid Terry,Astrid Terry,Trudy Torto-Alalibo,Joe Win,Zhanyou Xu,Hong-Bin Zhang,Igor V. Grigoriev,Igor V. Grigoriev,Daniel S. Rokhsar,Daniel S. Rokhsar,Jeffrey L. Boore +68 more
TL;DR: Comparison of the two species' genomes reveals a rapid expansion and diversification of many protein families associated with plant infection such as hydrolases, ABC transporters, protein toxins, proteinase inhibitors, and, in particular, a superfamily of 700 proteins with similarity to known oömycete avirulence genes.
Journal ArticleDOI
Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.
Maayan Levy,Christoph A. Thaiss,David Zeevi,Lenka Dohnalová,Gili Zilberman-Schapira,Jemal Ali Mahdi,Eyal David,Alon Savidor,Tal Korem,Yonatan Herzig,Meirav Pevsner-Fischer,Hagit Shapiro,Anette Christ,Alon Harmelin,Zamir Halpern,Eicke Latz,Eicke Latz,Richard A. Flavell,Ido Amit,Eran Segal,Eran Elinav +20 more
TL;DR: It is demonstrated that the microbiota-associated metabolites taurine, histamine, and spermine shape the host-microbiome interface by co-modulating NLRP6 inflammasome signaling, epithelial IL-18 secretion, and downstream anti-microbial peptide (AMP) profiles.
Journal ArticleDOI
Communication between viruses guides lysis–lysogeny decisions
Zohar Erez,Ida Steinberger-Levy,Ida Steinberger-Levy,Maya Shamir,Shany Doron,Avigail Stokar-Avihail,Yoav Peleg,Sarah Melamed,Azita Leavitt,Alon Savidor,Shira Albeck,Gil Amitai,Rotem Sorek +12 more
TL;DR: It is shown that viruses (phages) of the SPbeta group use a small-molecule communication system to coordinate lysis–lysogeny decisions, and that different phages encode different versions of the communication peptide, demonstrating a phage-specific peptide communication code for lysogenY decisions.
Journal ArticleDOI
Genome sequencing and mapping reveal loss of heterozygosity as a mechanism for rapid adaptation in the vegetable pathogen Phytophthora capsici.
Kurt Lamour,Joann Mudge,Daniel Gobena,Oscar P. Hurtado-Gonzales,Jeremy Schmutz,Alan Kuo,Neil A. Miller,Brandon J. Rice,Sylvain Raffaele,Liliana M. Cano,Arvind K. Bharti,Ryan S. Donahoo,Sabra Finley,Edgar Huitema,Jon Hulvey,Darren Platt,Asaf Salamov,Alon Savidor,Rahul Sharma,Remco Stam,Dylan Storey,Marco Thines,Joe Win,Brian J. Haas,Darrell L. Dinwiddie,Jerry Jenkins,James R. Knight,Jason P. Affourtit,Cliff Han,Olga Chertkov,Erika Lindquist,Chris Detter,Igor V. Grigoriev,Sophien Kamoun,Stephen F. Kingsmore +34 more
TL;DR: Overall, it appears that LOH may provide a rapid mechanism for fixing alleles and may be an important component of adaptability for P. capsici.