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Amerigo Iaconelli
Researcher at Catholic University of the Sacred Heart
Publications - 20
Citations - 2246
Amerigo Iaconelli is an academic researcher from Catholic University of the Sacred Heart. The author has contributed to research in topics: Weight loss & Insulin. The author has an hindex of 15, co-authored 20 publications receiving 1823 citations. Previous affiliations of Amerigo Iaconelli include Agostino Gemelli University Polyclinic & Sapienza University of Rome.
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Journal ArticleDOI
Bariatric-metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial
Geltrude Mingrone,Geltrude Mingrone,Simona Panunzi,Andrea De Gaetano,Caterina Guidone,Amerigo Iaconelli,Giuseppe Nanni,Marco Castagneto,Stefan R. Bornstein,Francesco Rubino +9 more
TL;DR: Surgery is more effective than medical treatment for the long-term control of obese patients with type 2 diabetes and should be considered in the treatment algorithm of this disease, however, continued monitoring of glycaemic control is warranted because of potential relapse of hyperglycaemia.
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Mechanisms of Recovery From Type 2 Diabetes After Malabsorptive Bariatric Surgery
Caterina Guidone,Melania Manco,Elena Valera-Mora,Amerigo Iaconelli,Donatella Gniuli,Andrea Mari,Giuseppe Nanni,Marco Castagneto,Menotti Calvani,Geltrude Mingrone +9 more
TL;DR: BPD determines a prompt reversibility of type 2 diabetes by normalizing peripheral insulin sensitivity and enhancing β-cell sensitivity to glucose, these changes occurring very early after the operation.
Journal ArticleDOI
Metabolic surgery versus conventional medical therapy in patients with type 2 diabetes: 10-year follow-up of an open-label, single-centre, randomised controlled trial.
Geltrude Mingrone,Geltrude Mingrone,Geltrude Mingrone,Simona Panunzi,Andrea De Gaetano,Caterina Guidone,Caterina Guidone,Amerigo Iaconelli,Amerigo Iaconelli,Esmeralda Capristo,Esmeralda Capristo,Ghassan Chamseddine,Stefan R. Bornstein,Francesco Rubino,Francesco Rubino +14 more
TL;DR: A 10-year follow-up study of an open-label, single-centre (tertiary hospital in Rome, Italy), randomised controlled trial, in which patients with type 2 diabetes (baseline duration >5 years; glycated haemoglobin [HbA1c] >7·0, and body-mass index ≥35 kg/m2) were randomly assigned to medical therapy, Roux-en-Y gastric bypass (RYGB), or biliopancreatic diversion (BPD) by a computerised system RE
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Gut microbiome-derived metabolites characterize a peculiar obese urinary metabotype
Riccardo Calvani,Alfredo Miccheli,Giorgio Capuani,A Tomassini Miccheli,Caterina Puccetti,Maurizio Delfini,Amerigo Iaconelli,Giuseppe Nanni,Geltrude Mingrone +8 more
TL;DR: Preliminary results confirmed that in humans the gut microflora metabolism is strongly linked to the obesity phenotype, and the typical obese metabotype is lost after weight loss induced by bariatric surgery.
Journal ArticleDOI
Influence of maternal obesity on insulin sensitivity and secretion in offspring.
Geltrude Mingrone,Melania Manco,Maria Elena Valera Mora,Caterina Guidone,Amerigo Iaconelli,Donatella Gniuli,Laura Leccesi,Chiara Chiellini,Giovanni Ghirlanda +8 more
TL;DR: The maternal genetic/epigenetic transmission shows a clear sexual dimorphism, with male offspring having a higher value of insulin sensitivity (although not statistically significant) associated with significantly higher insulin secretion than female offspring.