Amin R. Mazloom

TL;DR: It is demonstrated that mesenchymal stem cells (MSCs), identified using nestin expression, constitute an essential HSC niche component and are indicative of a unique niche in the bone marrow made of heterotypic stem-cell pairs.

TL;DR: It is identified how well-characterized surface markers, including MerTK and FcγR1 (CD64), along with a cluster of previously unidentified transcripts, were distinctly and universally associated with mature tissue macrophages and how these transcripts and the proteins they encode facilitated distinguishing macrophage from dendritic cells.

TL;DR: The ChEA database allowed us to reconstruct an initial network of transcription factors connected based on shared overlapping targets and binding site proximity, and it is shown how by combining the Connectivity Map with ChEA, it can rank pairs of compounds to be used to target specific transcription factor activity in cancer cells.

TL;DR: The purpose of this study was to extend the detection to include common sex chromosome aneuploidies (SCAs): [47,XXX], [45,X], [ 47,XXY], and [47-XYY] syndromes.

TL;DR: A novel method, referred to as SeqFF, for estimating the fetal DNA fraction in the plasma of pregnant women and to infer the underlying mechanism that allows for such statistical modeling is introduced.