A
Amit Gefen
Researcher at Tel Aviv University
Publications - 386
Citations - 15696
Amit Gefen is an academic researcher from Tel Aviv University. The author has contributed to research in topics: Adipogenesis & Heel. The author has an hindex of 55, co-authored 363 publications receiving 13702 citations. Previous affiliations of Amit Gefen include University of Pennsylvania & Sheba Medical Center.
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Journal ArticleDOI
Tensional homeostasis and the malignant phenotype.
Matthew J. Paszek,Nastaran Zahir,Kandice R. Johnson,Johnathon N. Lakins,Gabriela I. Rozenberg,Amit Gefen,Cynthia A. Reinhart-King,Susan S. Margulies,Micah Dembo,David Boettiger,Daniel A. Hammer,Valerie M. Weaver +11 more
TL;DR: It is found that tumors are rigid because they have a stiff stroma and elevated Rho-dependent cytoskeletal tension that drives focal adhesions, disrupts adherens junctions, perturbs tissue polarity, enhances growth, and hinders lumen formation.
Journal ArticleDOI
Are in vivo and in situ brain tissues mechanically similar
Amit Gefen,Susan S. Margulies +1 more
TL;DR: The concept that perfusion does not affect the stiffness of living cortical tissue is supported, and cortical gray matter on the parietal and frontal lobes can be considered homogenous.
Journal ArticleDOI
Assessment of mechanical conditions in sub-dermal tissues during sitting: A combined experimental-MRI and finite element approach
TL;DR: This is the first study to quantify sub-dermal tissue strain and stress distributions in sitting humans, in vivo, essential for understanding the aetiology of pressure sores, particularly those that were recently termed "deep tissue injury" at the US National Pressure Ulcer Advisory Panel 2005 Consensus Conference.
Journal ArticleDOI
Age-dependent changes in material properties of the brain and braincase of the rat
TL;DR: Observations of a stiffer brain and more compliant braincase in the immature rat compared with the adult rat will aid in the development of age-specific experimental models and in computational head injury simulations.
Journal ArticleDOI
A new pressure ulcer conceptual framework
Susanne Coleman,Jane Nixon,Justin Keen,Lyn Wilson,Elizabeth McGinnis,Carol Dealey,Nikki Stubbs,Amanda Farrin,Dawn Dowding,Jos M. G. A. Schols,Janet Cuddigan,Dan R. Berlowitz,Edward B. Jude,Peter Vowden,Lisette Schoonhoven,Lisette Schoonhoven,Dan L. Bader,Dan L. Bader,Amit Gefen,Cees W. J. Oomens,E Andrea Nelson +20 more
TL;DR: The new proposed conceptual framework provides the basis for understanding the critical determinants of pressure ulcer development and has the potential to influence risk assessment guidance and practice and to underpin future research to explore the role of individual risk factors conceptually and operationally.