scispace - formally typeset
Search or ask a question
Author

Amit Singh

Bio: Amit Singh is an academic researcher from National Institute of Technology, Patna. The author has contributed to research in topics: Digital watermarking & Watermark. The author has an hindex of 57, co-authored 640 publications receiving 13795 citations. Previous affiliations of Amit Singh include Ithaca College & Center for Infectious Disease Research and Policy.


Papers
More filters
Journal ArticleDOI
TL;DR: The discovery that the extract from the lemongrass plant, when reacted with aqueous chloroaurate ions, yields a high percentage of thin, flat, single-crystalline gold nanotriangles, which seem to grow by a process involving rapid reduction, assembly and room-temperature sintering of 'liquid-like' spherical gold nanoparticles.
Abstract: The optoelectronic and physicochemical properties of nanoscale matter are a strong function of particle size. Nanoparticle shape also contributes significantly to modulating their electronic properties. Several shapes ranging from rods to wires to plates to teardrop structures may be obtained by chemical methods; triangular nanoparticles have been synthesized by using a seeded growth process. Here, we report the discovery that the extract from the lemongrass plant, when reacted with aqueous chloroaurate ions, yields a high percentage of thin, flat, single-crystalline gold nanotriangles. The nanotriangles seem to grow by a process involving rapid reduction, assembly and room-temperature sintering of 'liquid-like' spherical gold nanoparticles. The anisotropy in nanoparticle shape results in large near-infrared absorption by the particles, and highly anisotropic electron transport in films of the nanotriangles.

1,473 citations

Journal ArticleDOI
TL;DR: A discussion of the FDA guidance on regulatory classification of pharmaceutical cocrystals of active pharmaceutical ingredients (APIs) was held in Manesar near Delhi, India, from February 2-4, 2012 as mentioned in this paper.
Abstract: The December 2011 release of a draft United States Food and Drug Administration (FDA) guidance concerning regulatory classification of pharmaceutical cocrystals of active pharmaceutical ingredients (APIs) addressed two matters of topical interest to the crystal engineering and pharmaceutical science communities: (1) a proposed definition of cocrystals; (2) a proposed classification of pharmaceutical cocrystals as dissociable “API-excipient” molecular complexes. The Indo–U.S. Bilateral Meeting sponsored by the Indo–U.S. Science and Technology Forum titled The Evolving Role of Solid State Chemistry in Pharmaceutical Science was held in Manesar near Delhi, India, from February 2–4, 2012. A session of the meeting was devoted to discussion of the FDA guidance draft. The debate generated strong consensus on the need to define cocrystals more broadly and to classify them like salts. It was also concluded that the diversity of API crystal forms makes it difficult to classify solid forms into three categories that...

734 citations

Journal ArticleDOI
TL;DR: A recent internet-based survey of 347 Austinites found that respondents perceive fewer crashes to be the primary benefit of autonomous vehicles (AVs), with equipment failure being their top concern as mentioned in this paper, and their average willingness to pay (WTP) for adding full (Level 4) automation ($7253) appears to be much higher than that for adding partial (Level 3) automation (3300) to their current vehicles.
Abstract: Technological advances are bringing connected and autonomous vehicles (CAVs) to the ever-evolving transportation system. Anticipating public acceptance and adoption of these technologies is important. A recent internet-based survey polled 347 Austinites to understand their opinions on smart-car technologies and strategies. Results indicate that respondents perceive fewer crashes to be the primary benefit of autonomous vehicles (AVs), with equipment failure being their top concern. Their average willingness to pay (WTP) for adding full (Level 4) automation ($7253) appears to be much higher than that for adding partial (Level 3) automation ($3300) to their current vehicles. Ordered probit and other model specifications estimate the impact of demographics, built-environment variables, and travel characteristics on Austinites’ WTP for adding various automation technologies and connectivity to their current and coming vehicles. It also estimates adoption rates of shared autonomous vehicles (SAVs) under different pricing scenarios ($1, $2, and $3 per mile), choice dependence on friends’ and neighbors’ adoption rates, and home-location decisions after AVs and SAVs become a common mode of transport. Higher-income, technology-savvy males, who live in urban areas, and those who have experienced more crashes have a greater interest in and higher WTP for the new technologies, with less dependence on others’ adoption rates. Such behavioral models are useful to simulate long-term adoption of CAV technologies under different vehicle pricing and demographic scenarios. These results can be used to develop smarter transportation systems for more efficient and sustainable travel.

603 citations

01 Jan 2016
TL;DR: In this paper, the authors conducted a survey with 347 Austinites to understand their opinions on smart-car technologies and strategies and found that respondents perceive fewer crashes to be the primary benefit of autonomous vehicles (AVs), with equipment failure being their top concern.
Abstract: Technological advances are bringing connected and autonomous vehicles (CAVs) to the ever- evolving transportation system. Anticipating the public acceptance and adoption of these technologies is important. A recent internet-based survey was conducted polling 347 Austinites to understand their opinions on smart-car technologies and strategies. Ordered-probit and other model results indicate that respondents perceive fewer crashes to be the primary benefit of autonomous vehicles (AVs), with equipment failure being their top concern. Their average willingness to pay (WTP) for adding full (Level 4) automation ($7,253) appears to be much higher than that for adding partial (Level 3) automation ($3,300) to their current vehicles. This study estimates the impact of demographics, built-environment variables, and travel characteristics on Austinites’ WTP for adding such automations and connectivity to their current and coming vehicles. It also estimates adoption rates of shared autonomous vehicles (SAVs) under different pricing scenarios ($1, $2, and $3 per mile), choice dependence on friends’ and neighbors’ adoption rates, and home-location decisions after AVs and SAVs become a common mode of transport. Higher-income, technology-savvy males, living in urban areas, and those who have experienced more crashes have a greater interest in and higher WTP for the new technologies, with less dependence on others’ adoption rates. Such behavioral models are useful to simulate long-term adoption of CAV technologies under different vehicle pricing and demographic scenarios. These results can be used to develop smarter transportation systems for more efficient and sustainable travel.

582 citations

Journal ArticleDOI
TL;DR: The aberrant exosomal process in cancer is conceptualized as being partially attributed to cancer specific differences in the endocytotic process of receptor recycling/degradation and plasma membrane remodeling and the function of the endosome as a signaling entity.

534 citations


Cited by
More filters
28 Jul 2005
TL;DR: PfPMP1)与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作�ly.
Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

18,940 citations

Christopher M. Bishop1
01 Jan 2006
TL;DR: Probability distributions of linear models for regression and classification are given in this article, along with a discussion of combining models and combining models in the context of machine learning and classification.
Abstract: Probability Distributions.- Linear Models for Regression.- Linear Models for Classification.- Neural Networks.- Kernel Methods.- Sparse Kernel Machines.- Graphical Models.- Mixture Models and EM.- Approximate Inference.- Sampling Methods.- Continuous Latent Variables.- Sequential Data.- Combining Models.

10,141 citations

Journal ArticleDOI
TL;DR: The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors.
Abstract: The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors. While the organization of the book is similar to previous editions, major emphasis has been placed on disorders that affect multiple organ systems. Important advances in genetics, immunology, and oncology are emphasized. Many chapters of the book have been rewritten and describe major advances in internal medicine. Subjects that received only a paragraph or two of attention in previous editions are now covered in entire chapters. Among the chapters that have been extensively revised are the chapters on infections in the compromised host, on skin rashes in infections, on many of the viral infections, including cytomegalovirus and Epstein-Barr virus, on sexually transmitted diseases, on diabetes mellitus, on disorders of bone and mineral metabolism, and on lymphadenopathy and splenomegaly. The major revisions in these chapters and many

6,968 citations

Journal ArticleDOI
TL;DR: A comprehensive review of current research activities that center on the shape-controlled synthesis of metal nanocrystals, including a brief introduction to nucleation and growth within the context of metal Nanocrystal synthesis, followed by a discussion of the possible shapes that aMetal nanocrystal might take under different conditions.
Abstract: Nanocrystals are fundamental to modern science and technology. Mastery over the shape of a nanocrystal enables control of its properties and enhancement of its usefulness for a given application. Our aim is to present a comprehensive review of current research activities that center on the shape-controlled synthesis of metal nanocrystals. We begin with a brief introduction to nucleation and growth within the context of metal nanocrystal synthesis, followed by a discussion of the possible shapes that a metal nanocrystal might take under different conditions. We then focus on a variety of experimental parameters that have been explored to manipulate the nucleation and growth of metal nanocrystals in solution-phase syntheses in an effort to generate specific shapes. We then elaborate on these approaches by selecting examples in which there is already reasonable understanding for the observed shape control or at least the protocols have proven to be reproducible and controllable. Finally, we highlight a number of applications that have been enabled and/or enhanced by the shape-controlled synthesis of metal nanocrystals. We conclude this article with personal perspectives on the directions toward which future research in this field might take.

4,927 citations