抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Probability Distributions.- Linear Models for Regression.- Linear Models for Classification.- Neural Networks.- Kernel Methods.- Sparse Kernel Machines.- Graphical Models.- Mixture Models and EM.- Approximate Inference.- Sampling Methods.- Continuous Latent Variables.- Sequential Data.- Combining Models.

Pattern Recognition and Machine Learning

The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors. While the organization of the book is similar to previous editions, major emphasis has been placed on disorders that affect multiple organ systems. Important advances in genetics, immunology, and oncology are emphasized. Many chapters of the book have been rewritten and describe major advances in internal medicine. Subjects that received only a paragraph or two of attention in previous editions are now covered in entire chapters. Among the chapters that have been extensively revised are the chapters on infections in the compromised host, on skin rashes in infections, on many of the viral infections, including cytomegalovirus and Epstein-Barr virus, on sexually transmitted diseases, on diabetes mellitus, on disorders of bone and mineral metabolism, and on lymphadenopathy and splenomegaly. The major revisions in these chapters and many

Harrison's Principles of Internal Medicine

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

Nanocrystals are fundamental to modern science and technology. Mastery over the shape of a nanocrystal enables control of its properties and enhancement of its usefulness for a given application. Our aim is to present a comprehensive review of current research activities that center on the shape-controlled synthesis of metal nanocrystals. We begin with a brief introduction to nucleation and growth within the context of metal nanocrystal synthesis, followed by a discussion of the possible shapes that a metal nanocrystal might take under different conditions. We then focus on a variety of experimental parameters that have been explored to manipulate the nucleation and growth of metal nanocrystals in solution-phase syntheses in an effort to generate specific shapes. We then elaborate on these approaches by selecting examples in which there is already reasonable understanding for the observed shape control or at least the protocols have proven to be reproducible and controllable. Finally, we highlight a number of applications that have been enabled and/or enhanced by the shape-controlled synthesis of metal nanocrystals. We conclude this article with personal perspectives on the directions toward which future research in this field might take.

Shape‐Controlled Synthesis of Metal Nanocrystals: Simple Chemistry Meets Complex Physics?

Author response: Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis

A field experiment was conducted at Karaikal “the tail end of Cauvery Delta Zone” during Navarai season, 2017 (spring) to identify the optimum dates of sowing and seed priming practices on dry matter production (DMP), yield and yield attributes under aerobic rice condition. The treatment variables were replicated thrice and further evaluated in factorial concept of RBD. The treatments consisted of three dates of sowing by weekly interval (started from Feb. 6, 2017) and five seed priming practices viz., water, 1% KCl, 2% moringa leaf extract, 1% pungam leaf extract and 5% cow dung slurry. Considering the seed priming practices, dry matter production, yield and yield attributes of aerobic rice were higher in seed primed with 2% moringa leaf extract which ultimately Original Research Article Pazhanisamy et al.; EJNFS, 12(3): 79-83, 2020; Article no.EJNFS.55500 80 produced higher grain yield (2256 kg ha) followed by the seeds primed with 5% cow dung slurry (1945.1 kg ha -1 ) and 1% pungam leaf extract (1912.3 kg ha -1 ), respectively. From the study, it has proved that seed priming @ 2% moringa leaf extract provides higher productivity of aerobic rice during Navarai season at Karaikal.

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Effect of Seed Priming Practices on Dry Matter Production, Yield and Yield Attributes of Aerobic Rice in Coastal Deltaic Region of Karaiakal

The creeping sinusoidal flow of non-Newtonian couple stress fluids in a two-dimensional porous medium channel with deformable walls, is investigated as a model of peristaltic physiological gastric transport. A mathematical model is developed which is also applicable to hemodynamics of diseased arteries. The assumptions of long wavelength and low Reynolds number approximation are employed for creeping (viscous-dominated) flow. Solutions for axial velocity, volumetric flow rate, pressure gradient and stream function are obtained. The influence of couple stress rheological parameter and permeability parameter on velocity profile, pressure gradient and stream lines patterns are computed with the aid of Mathematica Software.

Amit Singh

Papers

Author response: Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis

Effect of Seed Priming Practices on Dry Matter Production, Yield and Yield Attributes of Aerobic Rice in Coastal Deltaic Region of Karaiakal

A Study of Creeping Sinusoidal Flow of Bio-Rheological Fluids through a Two-Dimensional High Permeability Medium Channel

Solar charge controller

Comparison of lactation curve models used on monthly records of jersey-sahiwal crossbred cows